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COVID-19 and managing metabolic risk

Identifying metabolic risk is key in optimizing patient outcomes

A recent study published in the journal Diabetes Care links metabolic syndrome and severe outcomes from COVID-19, noting significant increases in intensive-care admissions, ventilation, acute respiratory distress syndrome (ARDS), and death among patients with metabolic syndrome vs those without metabolic syndrome.1

Deferred medical care is a continuing, alarming trend

Delaying care due to the COVID-19 pandemic may be increasing deaths for many conditions, including diabetes. Diabetes deaths rose to nearly 25% per 100,000 in 2020, the largest rise in the diabetes death rate in decades.2

Stay ahead of metabolic syndrome with enhanced diagnostic insights

Quest Diagnostics provides advanced testing to help you assess and care for patients with underlying metabolic risk.

Metabolic syndrome is defined by the National Heart, Lung, and Blood Institute as a group of factors increasing risk for heart disease, diabetes, stroke, and other health problems. Patients are said to have metabolic syndrome if they have 3 or more of the following conditions4:

Cardiometabolic testing for at-risk patients

There are a variety of testing approaches for metabolic risk based on the needs of individual patients. The chart below lists some of the tests Quest offers to help you power better patient outcomes.

Test name Test code CPT code(s)
Cardio IQ® Hemoglobin A1c
Includes Insulin, Intact, LC/MS/MS (93103), C-Peptide (372), Insulin Resistance Score
91732 83036
Diabetes, Newly Diagnosed and Monitoring Panela
Includes Glucose (483), HbA1c (496), Albumin-Creatinine Ratio, Urine (92739), Creatine, Serum (37091); Lipid Panel (7600) which includes Cholesterol, Total (334), Triglycerides (896), HDL Cholesterol (608), LDL-Cholesterol (calculated), Cholesterol/HDL Ratio (calculated), Non-HDL Cholesterol (calculated); Hepatic Function Panel (10256) which includes Protein, Total, Serum (754), Albumin (223), Globulin (calculated), Albumin/Globulin Ratio (calculated), Bilirubin, Total (287), Bilirubin, Direct (285), Indirect Bilirubin (calculated), Alkaline Phosphatase (234), Aspartate Aminotransferase (AST) (822), Alanine Aminotransferase (ALT) (823)
91712 82947, 83036,
80061, 80076,
82570, 82043,

aPanel components may be ordered separately.

Testing for insulin resistance (IR) can help patients take action

IR affects more than 60 million Americans.5 Testing can provide insights that can help patients prevent or delay the course of their prediabetes/diabetes.6

Test name Test code CPT code(s)
Cardio IQ® Insulin Resistance Panel with Scorea
Includes Insulin, Intact, LC/MS/MS (93103), C-Peptide (372), Insulin Resistance Score
36509 83525, 84681

Panel components may be ordered separately

Metabolic conditions and complications from

SARS-CoV-2 (COVID-19) infections

View our brochure to learn more about improving patient outcomes

through metabolic risk testing.



  1. Xie J, Zu Y, Alkhatib A, et al. Metabolic syndrome and COVID-19 mortality among adult black patients in New Orleans [published online ahead of print August 25, 2020]. Diabetes Care. doi:10.2337/dc20-1714
  2. Stobbe M. US deaths from heart disease and diabetes climbed amid COVID. Associated Press. June 9, 2021. Accessed June 10, 2021.
  3. American Diabetes Association, Thrivable. Effects of the COVID-19 pandemic on people with diabetes. December 2020 survey summary report. Accessed June 4, 2021.
  4. National Heart, Lung, and Blood Institute (NIH). Metabolic syndrome. Accessed October 1, 2020.
  5. American Heart Association (AHA). What is diabetes? Reviewed August 30, 2015. Accessed October 1, 2020.
  6. Reaven GM. The insulin resistance syndrome. Curr Atheroscler Rep. 2003;5(5):364-371. doi:10.1007/s11883-003-0007-0

The CPT® codes provided are based on American Medical Association guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.


Test codes may vary by location. Please contact your local laboratory for more information.