Precision Oncology Tests

LiquidSEQ^TM

Test Code

ABL1, ABL2, ABRAXAS1, ACVR1, ACVR1B, ADGRA2, AKT1, AKT2, AKT3, ALK, ALOX12B, ANKRD11, ANKRD26, APC, AR, ARAF, ARFRP1, ARID1A, ARID1B, ARID2, ARID5B, ASXL1, ASXL2, ATM, ATR, ATRX, AURKA, AURKB, AXIN1, AXIN2, AXL, B2M, BAP1, BARD1, BBC3, BCL10, BCL2, BCL2L1, BCL2L11, BCL2L2, BCL6, BCOR, BCORL1, BCR, BIRC3, BLM, BMPR1A, BRAF, BRCA1, BRCA2, BRD4, BRIP1, BTG1, BTK, CALR, CARD11, CASP8, CBFB, CBL, CCN6, CCND1, CCND2, CCND3, CCNE1, CD274, CD276, CD74, CD79A, CD79B, CDC73, CDH1, CDK12, CDK4, CDK6, CDK8, CDKN1A, CDKN1B, CDKN2A, CDKN2B, CDKN2C, CEBPA, CENPA, CHD2, CHD4, CHEK1, CHEK2, CIC, COP1, CREBBP, CRKL, CRLF2, CSF1R, CSF3R, CSNK1A1, CTCF, CTLA4, CTNNA1, CTNNB1, CUL3, CUX1, CXCR4, CYLD, DAXX, DCUN1D1, DDR2, DDX41, DHX15, DICER1, DIS3, DNAJB1, DNMT1, DNMT3A, DNMT3B, DOT1L, E2F3, EED, EGFL7, EGFR, EIF1AX, EIF4A2, EIF4E, ELOC, EML4, EMSY, EP300, EPCAM, EPHA3, EPHA5, EPHA7, EPHB1, ERBB2, ERBB3, ERBB4, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERG, ERRFI1, ESR1, ETS1, ETV1, ETV4, ETV5, ETV6, EWSR1, EZH2, FAM123B, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FAS, FAT1, FBXW7, FGF1, FGF10, FGF14, FGF19, FGF2, FGF23, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, FGFR1, FGFR2, FGFR3, FGFR4, FH, FLCN, FLI1, FLT1, FLT3, FLT4, FOXA1, FOXL2, FOXO1, FOXP1, FRS2, FUBP1, FYN, GABRA6, GATA1, GATA2, GATA3, GATA4, GATA6, GEN1, GID4, GLI1, GNA11, GNA13, GNAQ, GNAS, GPS2, GREM1, GRIN2A, GRM3, GSK3B, H1-2, H2BC5, H3-3A, H3-3B, H3-4, H3-5, H3C1, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3C10, H3C11, H3C12, H3C13, H3C14, H3C15, HGF, HLA-A, HLA-B, HLA-C, HNF1A, HNRNPK, HOXB13, HRAS, HSD3B1, HSP90AA1, ICOSLG, ID3, IDH1, IDH2, IFNGR1, IGF1, IGF1R, IGF2, IKBKE, IKZF1, IL10, IL7R, INHA, INHBA, INPP4A, INPP4B, INSR, IRF2, IRF4, IRS1, IRS2, JAK1, JAK2, JAK3, JUN, KAT6A, KDM5A, KDM5C, KDM6A, KDR, KEAP1, KEL, KIF5B, KIT, KLF4, KLHL6, KMT2B, KMT2C, KMT2D, KRAS, LAMP1, LATS1, LATS2, LMO1, LRP1B, LYN, LZTR1, MAGI2, MALT1, MAP2K1, MAP2K2, MAP2K4, MAP3K1, MAP3K13, MAP3K14, MAP3K4, MAPK1, MAPK3, MAX, MCL1, MDC1, MDM2, MDM4, MED12, MEF2B, MEN1, MET, MGA, MITF, MLH1, MLL, MLLT3, MPL, MRE11, MSH2, MSH3, MSH6, MST1, MST1R, MTOR, MUTYH, MYB, MYC, MYCL, MYCN, MYD88, MYOD1, NAB2, NBN, NCOA3, NCOR1, NEGR1, NF1, NF2, NFE2L2, NFKBIA, NKX2-1, NKX3-1, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NPM1, NRAS, NRG1, NSD1, NTRK1, NTRK2, NTRK3, NUP93, NUTM1, PAK1, PAK3, PAK5, PALB2, PARP1, PAX3, PAX5, PAX7, PAX8, PBRM1, PDCD1, PDCD1LG2, PDGFRA, PDGFRB, PDK1, PDPK1, PGR, PHF6, PHOX2B, PIK3C2B, PIK3C2G, PIK3C3, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIK3R3, PIM1, PLCG2, PLK2, PMAIP1, PMS1, PMS2, PNRC1, POLD1, POLE, PPARG, PPM1D, PPP2R1A, PPP2R2A, PPP6C, PRDM1, PREX2, PRKAR1A, PRKCI, PRKDC, PRKN, PRSS8, PTCH1, PTEN, PTPN11, PTPRD, PTPRS, PTPRT, QKI, RAB35, RAC1, RAD21, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54L, RAF1, RANBP2, RARA, RASA1, RB1, RBM10, RECQL4, REL, RET, RHEB, RHOA, RICTOR, RIT1, RNF43, ROS1, RPS6KA4, RPS6KB1, RPS6KB2, RPTOR, RUNX1, RUNX1T1, RYBP, SDHA, SDHAF2, SDHB, SDHC, SDHD, SETBP1, SETD2, SF3B1, SH2B3, SH2D1A, SHQ1, SLIT2, SLX4, SMAD2, SMAD3, SMAD4, SMARCA4, SMARCB1, SMARCD1, SMC1A, SMC3, SMO, SNCAIP, SOCS1, SOX10, SOX17, SOX2, SOX9, SPEN, SPOP, SPTA1, SRC, SRSF2, STAG1, STAG2, STAT3, STAT4, STAT5A, STAT5B, STK11, STK40, SUFU, SUZ12, SYK, TAF1, TBX3, TCF3, TCF7L2, TENT5C, TERC, TERT, TET1, TET2, TFE3, TFRC, TGFBR1, TGFBR2, TMEM127, TMPRSS2, TNFAIP3, TNFRSF14, TOP1, TOP2A, TP53, TP63, TRAF2, TRAF7, TSC1, TSC2, TSHR, U2AF1, VEGFA, VHL, VTCN1, WT1, XIAP, XPO1, XRCC2, YAP1, YES1, ZBTB2, ZBTB7A, ZFHX3, ZNF217, ZNF703, and ZRSR2. Includes TMB and MSI analysis.

14308

Solid TumorSEQ^TM

Test Code

Includes assessment of all DNA variant types for all genes listed for LiquidSEQ™ above, with additional testing of 55 genes for RNA fusions

ABL1, AKT3, ALK, AR, AXL, BCL2, BRAF, BRCA1, BRCA2, CDK4, CSF1R, EGFR, EML4, ERBB2, ERG, ESR1, ETS1, ETV1, ETV4, ETV5, EWSR1, FGFR1, FGFR2, FGFR3, FGFR4, FLI1, FLT1, FLT3, JAK2, KDR, KIF5B, KIT, MET, MLL, MLLT3, MSH2, MYC, NOTCH1, NOTCH2, NOTCH3, NRG1, NTRK1, NTRK2, NTRK3, PAX3, PAX7, PDGFRA, PDGFRB, PIK3CA, PPARG, RAF1, RET, ROS1, RPS6KB1, and TMPRSS2 (splice site analysis also performed for AR, EGFR, and MET). Includes TMB and MSI analysis

143089

Test name

Test Code

LungSEQ Panel

Includes KT1, ALK, BRAF, EGFR, ERBB2, KRAS, MAP2K1, NRAS,
PIK3CA, and PTEN

36915

LungSEQ Concurrent Panel, without PD-L1a

Includes LK, AKT1, BRAF, EGFR, ERBB2, KRAS, MAP2K1, NRAS, PIK3CA, and PTEN. Also includes: ALK Rearrangement, RET Rearrangement, ROS1 Rearrangement, and MET Amplification

12184

ColonSEQ Panel

Includes BRAF, KRAS, NRAS, MSI (PCR), PIK3CA, PTEN

36918

ColonSEQPlus Panel

Includes APC, BRAF, CTNNB1, EGFR, ERBB2 (HER2), FBXW7, KRAS, MET, NRAS, PIK3CA, PTEN, SMAD4, TP53 with microsatellite instability (MSI)

36919

MelanomaSEQ Panel

Includes BRAF, c-KIT, NRAS

36914

MelanomaSEQPlus Panel

Includes BRAF, c-KIT, CTNNB1, GNA11, GNAQ, GNAS, HRAS, KRAS, NRAS, PIK3CA, PTEN

36912

Thyroid Mutation Cancer Panel

Includes BRAF Mutation Analysis, RAS Mutation Analysis, RET/PTC Rearrangement, PAX8/PPAR[gamma] Translocation

90469

Test name

Test Code

c-KIT Mutation Analysis, PCR

19961

PIK3CA Mutation Analysis

16897

NRAS Mutation Analysis (exons 1&2 - DNA sequencing)

16818

KRAS Mutation Analysis (exons 1&2 - DNA

16510

BRAF Mutation Analysis

16767

BRAF Mutation Analysis, Papillary Thyroid Cancer

90477

RAS MUTATION ANALYSIS, THYROID CANCER

90479

RET/PTC Rearrangement Thyroid Cancer

90473

PAX8/PPAR[gamma] Translocation, Thyroid Cancer

90474

MELANOMA, BRAF V600 MUTATION, COBAS

90956

EGFR MUTATION, COBAS V2, LIQUID BIOPSY

94718

Epidermal Growth Factor Receptor (EGFR) Mutation, Cobas V2, Solid Tumor

94719

PDGFRA Mutation Analysis

16859

Comprehensive Hereditary Cancer Panel

Test Code

APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN1B, CDKN2A (p16, p14), CHEK2, DICER1, EGFR, EPCAM, FANCA, FANCC, FANCM, FH, FLCN, GALNT12, GREM1, HOXB13, MAX, MEN1, MET, MITF, MLH1, MRE11, (MRE11A), MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, POT1, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RECQL, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMARCA4, SMAD4, STK11, SUFU, TMEM127, TP53, TSC1, TSC2, VHL, XRCC2

38600

Guideline Based Hereditary Cancer Panel

Test Code

APC, ATM, AXIN2, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A (p16, p14), CHEK2, EPCAM, GREM1, HOXB13, MLH1, MSH2, MSH3, MSH6, MUTYH, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53

38611

Hereditary Breast Cancer Panel

Test Code

ATM, BARD1, BRCA1, BRCA2, CHEK2, CDH1, EPCAM, MLH1, MSH2, MSH6, NF1, PALB2, PMS2, PTEN, RAD51C, RAD51D, STK11, TP53

38621

Hereditary Colorectal Cancer Panel

Test Code

APC, AXIN2, BMPR1A, CDH1, CHEK2, EPCAM, GREM1, MLH1, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, SMAD4, STK11, TP53

38631

Test name

Test code

APC Sequencing and Deletion/Duplication

93797

ATM Sequencing and Deletion/Duplication

38802

BAP1 Sequencing and Deletion/Duplication

38803

BLM Sequencing and Deletion/Duplication

38804

CDH1 Sequencing and Deletion/Duplication

92568

CDKN2A Sequencing and Deletion/Duplication

93939

CHEK2 Sequencing and Deletion/Duplication

93940

Lynch Syndrome, MSH2 Sequencing and Deletion/Duplication (Including EPCAM)

91471

FH Gene Sequencing and Deletion/Duplication

38805

FLCN Sequencing and Deletion/Duplication

38806

HOXB13 Sequencing and Deletion/Duplication

38807

MEN1 Sequencing and Deletion/Duplication

93942

MITF Gene Analysis

38808

Lynch Syndrome, MLH1 Sequencing and Deletion/Duplication

91460

Lynch Syndrome, MSH6 Sequencing and Deletion/Duplication

91458

MUTYH Sequencing and Deletion/Duplication

93944

NF1 Sequencing and Deletion/Duplication

93941

PALB2 Sequencing and Deletion/Duplication

92571

Lynch Syndrome, PMS2 Sequencing and Deletion/Duplication

91457

PTEN Sequencing and Deletion/Duplication

92566

RET Sequencing and Deletion/Duplication

93796

SMARCA4 Sequencing and Deletion/Duplication

38809

STK11 Sequencing and Deletion/Duplication

92565

Li-Fraumeni Syndrome, TP53 Sequencing and Deletion/Duplication

92560

VHL Sequencing and Deletion/Duplication

93943

Test Code

ABCG2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, CYP4F2, DPYD F5, HLA-A*31:01, HLA-B*15:02, HLA-B*57:01, HLA-B*58:01, IFNL3, NAT2, NUDT15, SLCO1B1, TPMT, UGT1A1, VKORC1

14271

Test Code

c.1905+1G>A, c.295_298delTCAT, c.703C>T, c.2983G>T, c.1156G>T, c.1679T>G, c.557A>G, c.2846A>T, c.61C>T, c.1129-5923C>G, c.2279C>T, c.868A>G

18753