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Quest Diagnostics

Colorectal Cancer Screening

Colorectal cancer that is caught in the early stages has a 5-year survival rate of over 90%.1 Yet, only 39% of cases2 are diagnosed in early stages due to low screening rates. When this disease spreads to distant organs, the 5-year survival rate drops to 11%.3

Easy-to-use, in-home colorectal screening

InSure® ONE™ is a convenient, at-home fecal immunochemical test (FIT) that aids in the detection of lower gastrointestinal bleeding that may be caused by colorectal cancer or other lower gastrointestinal disorders.*

 

Studies show that InSure ONE testing helps more people actually get the screening they need. FIT testing is supported by medical guidelines, including the American Cancer Society, the American College of Gastroenterology, and the US Preventive Services Task Force for early detection of colorectal cancer 3,5,6,8

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Accurate colorectal screening

InSure ONE qualitatively detects human hemoglobin from blood in fecal samples,6 which may be an indication of lower gastrointestinal bleeding associated with disorders such as diverticulitis, ulcerative colitis, polyps, colorectal cancers, or large adenomas that bleed. The assay uses monoclonal antibodies to capture human hemoglobin on a test strip.

The InSure® ONE™ kit

InSure ONE comes in a patient-friendly kit that contains everything necessary to collect a water-based sample and package it for shipping in an enclosed self-mailing envelope.

  • Test requisition        
  • Patient instructions for use
  • A test card
  • 2 long-handled brushes
  • 2 waste bags

Please contact your Quest Diagnostics sales representative for instructions in additional languages.


 

Patient-friendly collection

The convenient water-based collection method uses a unique, patented brush sampling that doesn’t require any stool collection or handling. There are no dietary or medicinal restrictions. Patients collect 2 water-based samples from a single bowel movement. This patient-friendly approach to testing is associated with up to 66% greater patient compliance.7


 

Every kit returned could save a life by early detection

Our InSure® ONE™ integrated reminder program helps encourage test compliance by sending reminder messages to patients to complete and return their collection kit. Electronic orders for InSure ONE placed in Quanum® Lab Services Manager or your EMR interface are eligible to receive reminders.

Who should be screened with InSure ONE?

Distribute kits to average-risk patients aged 45+ during annual wellness visits.

 

 

 

 

 

Get started with InSure® ONE™ in just 2 easy steps

1. Order InSure ONE kits using Quanum Lab Services Manager using test code 11290

If you don’t have a Quanum account, create one in less than 5 minutes by clicking here. If you would prefer to order kits over the phone, please call 1.866.MYQUEST (1.866.697.8378) and state “supplies” upon connection for assistance.

Quest will ship the kits to your practice at no cost, based on usage and test completion.



2. Print a copy of the requisition

A completed requisition form from Quanum Lab Services Manager or your EMR should be printed and placed in the business reply envelope found inside the test kit envelope prior to the patient leaving the office.

Test name Test Code
Fecal Globin by Immunochemistry (InSure®) 11290

* InSure ONE is a fecal immunochemical test (FIT) that qualitatively detects human hemoglobin from blood in fecal samples. The samples will generally be collected by the test subject at home and the test developed at laboratories or professional offices. The InSure ONE test is used to aid in the detection of lower gastrointestinal bleeding.4

 

​References:

  1. National Cancer Institute. Cancer stat facts: colorectal cancer. Accessed July 31, 2020. https://seer.cancer.gov/statfacts/html/colorect.html
  2. American Cancer Society. Colorectal cancer facts & figures 2017-2019. Published 2017. Accessed July 31, 2020. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/colorectal-cancer-facts-and-figures/colorectal-cancer-facts-and-figures-2017-2019.pdf
  3. InSure® ONE™. K170548 – Instructions for use. Quest Diagnostics; 2017.
  4. InSure® FIT. F002457 Fecal immunochemical test immunoassay for human hemoglobin in stool. Product instructions. Enterix; 2011.
  5. US Preventive Services Task Force, Bibbins-Domingo K, Grossman DC, et al. Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. JAMA. 2016;315(23):2564-2575. doi:10.1001/jama.2016.5989
  6. Cole SR, Young GP, Esterman A, et al. A randomised trial of the impact of new faecal haemoglobin test technologies on population participation in screening for colorectal cancer. J Med Screen. 2003;10(3):117-122. doi:10.1177/096914130301000304
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For assistance with questions about the testing process or locations, call 1.866.MYQUEST (1.866.697.8378)

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Quest® is the brand name used for services offered by Quest Diagnostics Incorporated and its affiliated companies. Quest Diagnostics Incorporated and certain affiliates are CLIA-certified laboratories that provide HIPAA-covered services.  Other affiliates operated under the Quest® brand, such as Quest Consumer Inc., do not provide HIPAA-covered services. 

 

Quest®, Quest Diagnostics®, any associated logos, and all associated Quest Diagnostics registered or unregistered trademarks are the property of Quest Diagnostics. All third-party marks—® and ™—are the property of their respective owners. © 2025 Quest Diagnostics Incorporated. All rights reserved. Image content features models and is intended for illustrative purposes only.