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Screening for STI - females aged 15-24

May be included in a universal screening with opt-out program, per 2021 CDC guidelines2

Universal screening with opt-out for CT/NG

Notify ALL female patients ages 15-24 that CT/NG screening is included in their annual visits unless specifically declined2

Your adolescent and young adult female patients need greater protection

As of 2018, 1 in 2 STIs was acquired by people under the age 251
More than half of females ages 15–24 are reluctant to bring up STIs with their provider3
Most female patients <25 years of age want their doctors to automatically test them for CT and NG once a year4

Universal screening with opt-out makes it easier to protect your patients

 

From the 2021 CDC Guidelines2

When the patient is notified that testing will be performed unless the patient declines, regardless of reported sexual activity, this is known as ‘opt-out screening.’ Providers might consider opt-out chlamydia and gonorrhea screening for adolescent and young adult females during clinical encounters.

 

Cost-effectiveness analyses indicate that opt-out chlamydia screening among adolescent and young adult females might:

•  Substantially increase screening
•  Be cost-saving
•  Identify infections among patients who do not disclose sexual behavior

Read the latest guidelines

 

Universal screening with opt-out for females 15-24 can decrease CT prevalence by more than 55%5


Commit to universal screening with opt-out for CT/NG for your adolescent and young-adult patients

Universal screening with opt-out can be integrated into OBGYN practices without disrupting the practice workflow. By increasing screening, you can help ensure that your at-risk patients can be identified and treated earlier—reducing their risk of developing PID and ultimately protecting their fertility.

As part of mandatory reporting requirements to identify potential abuse, when testing minors under the age of consent, healthcare professionals may be required in certain jurisdictions to report positive results of sexually transmitted disease testing to authorities.

Access resources and insights to help you integrate universal sreening with opt-out

Hear Dr. Monique Rainford, OBGYN discuss the difference between universal screening with opt-out for all female patients ages 15-24, and offering screening and the benefits of early detection.

Watch the video

This webinar by nurse practitioner Dr. Randee Masciola offers practical tips for adopting universal screening with opt-out and understanding how it supports patient trust.

Watch the video

Help identify and care for your high-risk patients.
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Ordering the right test at the right time

Screening for STIs is recommended for women at all stages of their lives. The intuitive tables below can help guide your discussions for patient-focused testing recommendations.

Chlamydia/Neisseria gonorrhoeae

Test code 11363

  • Annual screening is recommended for females ages 15-248
  • Screening is recommended for women 25 and over at increased risk8a
  • Panel components can be ordered separately:
    • Test code 11361—Chlamydia trachomatis RNA, TMA, Urogenital
    • Test code 11362—Neisseria gonorrhoeae RNA, TMA, Urogenital

Trichomonas Vaginalis

Test codes 19550, 90521

  • Screening for Trichomonas vaginalis should be performed on women seeking care for vaginal discharge8
  • Screening might be considered for women receiving care in high-prevalence settings and for asymptomatic persons at increased riska for infection
  • The use of highly sensitive and specific tests, such as NAAT, are recommended over less-sensitive methods including wet-mount microscopy8b

Chlamydia Trachomatis

Test code 11363

  • All pregnant women aged <25 years or older women at increased risk for infection should be screened during their first prenatal visits8
  • Those aged <25 years and those at increased riska for chlamydia should be retested during their third trimester8
  • Those found to have chlamydial infection should have a test-of-cure (preferably by NAAT) 3 to 4 weeks after treatment and retested at 3 months8

Neisseria Gonorrhoeae

Test code 11363

  • All pregnant women aged <25 years and older women at increased riska for gonorrhea should be screened at their first prenatal visits8
  • Women found to have gonococcal infection should be treated immediately and retested within 3 months8
  • Those who remain at high riska for gonococcal infection should be retested during the third trimester8

Trichomonas Vaginalis

Test codes 19550, 90521

  • Women who report symptoms should be evaluated and treated appropriately
  • Evidence does not support routine screening for Trichomonas vaginalis in asymptomatic pregnant women

Chlamydia/Neisseria gonorrhoeae

Test code 11363

  • For sexually active individuals, screen at first HIV evaluation, and at least annually thereafter8
  • Panel components can be ordered separately:
    • Test code 11361—Chlamydia trachomatis RNA, TMA, Urogenital
    • Test code 11362—Neisseria gonorrhoeae RNA, TMA, Urogenital
  • Specific testing includes NAAT for C trachomatis at the anatomic site of exposure as the preferred approach

Trichomonas Vaginalis

Test codes 19550, 90521

  • Recommended for sexually active women at entry to care and at least annually thereafter8

Chlamydia Trachomatis

Test code 11363

  • Women and men should be retested approximately 3 months after chlamydia treatment8c
  • If retesting at 3 months is not possible, you should retest whenever your patient next receives medical care in the 12 months following the initial treatment8

Neisseria Gonorrhoeae

Test code 11363

  • Patients with symptoms that persist after treatment should be evaluated by culture for gonorrhea and for antimicrobial susceptibility8
  • Clinicians should advise patients with gonorrhea to be retested 3 months after treatment or when they next seek medical care within the following 12 months8

Trichomonas Vaginalis

Test codes 19550, 90521

  • Retesting for Trichomonas vaginalis is recommended for all sexually active women within 3 months following initial treatment regardless of whether they believe their sex partners were treated8

a People with increased risk are women who have had a history of sexually transmitted diseases (STDs), exchange sex for payment, or use injection drugs; and men and women with a new sex partner, more than 1 sex partner, a sex partner with concurrent partners, or a sex partner who has a sexually transmitted infection.

b When highly sensitive testing (eg, nucleic acid amplification test [NAAT]) is not feasible, a testing algorithm (eg, wet mount first, followed by NAAT if negative) can improve diagnostic sensitivity.

c The use of chlamydial NAATs at <3 weeks after completion of therapy is not recommended because the continued presence of nonviable organisms can lead to false-positive results.3

These helpful resources can provide additional information and guidelines:


​References:

  1. CDC estimates 1 in 5 people in the U.S. have a sexually transmitted infection. Centers for Disease Control and Prevention. Published January 25, 2021. Accessed March 12, 2022. https://www.cdc.gov/media/releases/2021/p0125-sexualy-transmitted-infection.html
  2. CDC. Sexually Transmitted Infections Treatment Guidelines, 2021. Accessed March 14, 2022. https://www.cdc.gov/std/treatment-guidelines/STI-Guidelines-2021.pdf
  3. CDC. CDC fact sheet: information for teens and young adults: staying healthy and preventing STDs. Accessed March 14, 2022. https://www.cdc.gov/std/life-stages-populations/stdfact-teens.htm
  4. Quest Diagnostics. Universal STI testing research among young women and moms: topline report. December 2017
  5. Owusu-Edusei K Jr, Hoover KW, Gift TL. Cost-effectiveness of opt-out chlamydia testing for high-risk young women in the US. Am J Prev Med. 2016;51(2):216-224. doi:10.1016/j.amepre.2016.01.007
  6. CDC. Sexually transmitted disease preventive services coverage. Accessed March 14, 2022. https://www.cdc.gov/nchhstp/preventionthroughhealthcare/preventiveservices/std.htm

 

Test codes may vary by location. Please contact your local laboratory for more information.


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