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Your Cardio IQ® report: an in-depth assessment of CVD risk to help individualize treatment

Cardio IQ® Testing can offer a more complete picture of your patients’ cardiovascular health. Click on a link below to learn more about the Cardio IQ® Report, managing residual risk through testing, or how to order Cardio IQ® Testing. Or simply scroll down to read the entire section.

Your Cardio IQ® Report:

An in-depth assessment of CVD risk to help individualize treatment

The Cardio IQ® Report provides an in-depth assessment of cardiovascular risks to help you recommend the ideal individualized treatment option for your patients.

Our report is simple, yet comprehensive. It is:

  • Color-coded to display progressive risk values versus goal using “optimal,” “moderate,” and “high-risk” categories
  • grouped by functional categories
  • inclusive of history from prior Cardio IQ® Report for evaluating progress

Note: This example represents the resulting report for an order of Cardio IQ® ASCVD Risk Panel with Scores, which includes lipid panel components and ASCVD risk scores.

Order Cardio IQ® testing for a more advanced approach to lipid subclass characterization.

At Quest Diagnostics, we are passionate about uncovering hidden risk that may benefit patients with:

  • Established CVD
  • Diabetes
  • Hypertension
  • Metabolic syndrome, as defined by having any 3 of the following 5 conditions: central obesity, elevated triglycerides, low HDL-C, elevated blood pressure, elevated plasma glucose
  • Elevated LDL-C >190 mg/dL
  • >5% Estimated ASCVD risk
  • Other traditional CVD risk factors, including:

Age (men >45 years; postmenopausal women), family history of premature onset of CVD, unhealthy diet and stress, excessive alcohol intake, smoking, obesity, low HDL-C

Managing residual risk with advanced insights

Advanced cardiovascular testing provides actionable information to individualize treatment options:

  • Initiate/intensify statin therapy
  • Identify opportunities for adjunct therapy
  • Set diet, exercise, and lifestyle targets
Test Results Relative Risk Treatment Options Goal
Elevated LDL Cholesterol 1.6x8
  • Diet and Exercise
  • Fibres, Niacin, Statins, Bile Acid Sequestrants
LDL Cholesterol < 100 mg/dl
LDL Cholesterol reduction 30% to <50%
Moderate intensity statin dose group
LDL Cholesterol reduction >50%
High intensity statin dose group
Elevated LDL Triglycerides 1.7-4.0x8
  • Diet and Exercise
  • Fibrates,Niacin, Statin, Fish Oil
Triglycerides <150 mg/dL
Elevated LDL Particle Number 1.4-2.39*,10,11
  • Diet and Exercise
  • Fibrates, Niacin, Statins
1260 nmol/L
Elevated Small LDL Particles 1.3-2.19*,10,11
  • Diet and Exercise
  • Fibrates, Niacin, Statins
Small <162 nmol/L
Elevated Medium LDL Particles 1.4-2.239*,10,11
  • Diet and Exercise
  • Fibrates, Niacin, Statins
Medium <201 nmol/L
Suboptimal Large LDL 1.8x9*
  • Diet and Exercise
  • Niacin
Large HDL >9386 nmol/L
Elevated Apo B Particles 2.0-2.5x12
  • Diet and Exercise
  • Fibres, Niacin, Statins, Bile Acid Sequestrants
Apo B <80 mg/dL
Elevated Lp(a) 1.5-5.3x13
  • Niacin
  • Fenofibrates(limited effect)
Lp(a) <75 nmol/L
Elevated hs-CRP 1.5-2.0x6
  • Diet and Exercise
  • Fibrates, Niacin, Statins
hs-CRP<1 mg/L
Elevated Lp-PLA 2 2x CHD event†7
(MI, coronary revascularization or CHD-related death) at 5 years
  • Diet and Exercise
  • Fibrates, Niacin, Statins, Fish Oil
Lp-PLA2 <= 123 nmol/min/mL

* Expected risk of highest tertile versus lowes tertile assuming measure is normally distributed and risk incresed linearly.

† The risk associated with elevated Lp-PLA2 levels is substantially increased in patients when both Lp-PLA2 and CRP are elevated.

‡ For more information on treatment options and goals per test, please see the Test Guide and/ or Test Summary psotede within the specific test's section on

Consider ordering Cardio IQ®: A more advanced approach to lipid subclass characterization 

Ordering Information
Test Name Test Code* CPT Code*
Advanecd Lipid Panel (Includes the below components except for 91737(X),94218(X)) 92145(X) 80061,83704,82172,83695
Advanced Lipd Panel with Inflammation

Cardio IQ Lipid Panel with Reflex to Direct LDL**





Cardio IQ Lipoprotein Fractionation, Ion Mobility 91604(X) 83704
CardioIQ Apolipoprotein B 91726(X) 82172
Cardio IQ Lipoprotein (a) 91729(X) 83695
Cardio IQ hs CRP 91737(X) 86141
Cardio IQ Lp-PLA2 94218(X) 83698

*Testcodes may vary by location. Please contact your laboratory for maore information. The CPT codes provided are based on AMA Guidelines and are for informational purposes only. CPT coding is the sole responsability of the billing party. Please direct any questions regarding coding to the payer being billed.

** Lipid panel components may be ordered separately: Cholesterol, Total 91717(X)/334 (CPT 82465); Triglycerides 91718(X)/896 (CPT 84478); HDL Cholesterol 91719(Xy608(CPT83718)). If triglyceride result is > 400mg/dL, Direct LDL Cholesterol will be performed at an additional charge (CPT 83721).

Discover more tests that may help you deliver customized treatment to your patients at risk for cardiovascular disease.