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Endocrine disorders

Insights that can help you diagnose and manage endocrine disorders

Managing patients with endocrine disorders is complex, and many people go undiagnosed: Among those with thyroid disorders, for example, only 4 in 10 are aware of their condition.1

By having the right test for the right patient, you can make more informed decisions faster and with greater confidence. Specialized assays and those performed using specific and sensitive mass spectrometry detection methods can help you better navigate the diagnostic subtleties of an endocrine disorder.  

With a legacy of expertise in endocrine lab diagnostics, Quest Diagnostics offers an extensive menu of guideline-based testing across the endocrine disorder spectrum. We provide straightforward test categorization, making it easier for you to identify the tests you need for any and every patient.

A comprehensive range of testing

Guideline-based thyroid testing

The spectrum of thyroid disorders is wide and far-reaching, including a broad range of etiologies, manifestations, and potential therapies. With an extensive menu of tests aligned to the most recent clinical practice guidelines—including the American Thyroid Association (ATA) and the American Association of Clinical Endocrinologists (AACE)—Quest Diagnostics can help you diagnose, treat, monitor, and prevent complications for these common disorders affecting 20 million people in the US.1

The most frequently diagnosed disorders include hypothyroidism and hyperthyroidism, which are each commonly caused by underlying immune disorders, including Graves disease and Hashimotos disease. For these conditions, ATA/AACE guidelines recommend screening symptomatic patients. Asymptomatic women over 50 should receive hypothyroid testing, and certain patients—such as those with autoimmune diseases or a family history of thyroid concerns—may also benefit from testing.2,3

Learn more about thyroid testing.

A broad range of sex hormone testing

Abnormalities in reproductive hormones can lead to a spectrum of difficulties across both sexes—from low testosterone in males to polycystic ovary syndrome (PCOS) in females. Our extensive menu of testing empowers diagnostic decision-making while supporting patients on these challenging personal journeys.

Screen for pituitary hormone deficiency, growth hormone antibodies, and other abnormalities with more than 20 different tests to help diagnose and manage growth disorders.

Deficiencies in Vitamin D and other conditions linked to bone and mineral metabolism can lead to a wide range of musculoskeletal concerns, as well as heart disease, hypertension, diabetes, and cancer. Testing can inform diagnostic plans as well as manage problems once diagnosed. 

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Screen for parathyroid hormone (PTH) antibodies, calcium, and more with over a dozen parathyroid metabolism testing options to help inform disorder diagnosis and management.

Identify a range of adrenal disorders including congenital adrenal hyperplasia and Addison’s disease, and assess adrenocortical function and catecholamines for the diagnostic insights you need. 

Check for follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), luteinizing hormone (LH), and more with our expansive menu of tests to diagnose and manage hypothalamic and pituitary disorders.

Make a more confident multiple endocrine neoplasia (MEN) diagnosis with DNA sequencing and dozens of screens for calcium, insulin, and more.

Determine how a patient’s body reacts to stimuli such as glucose with a broad menu of dynamic tests that can diagnose a wide range of endocrine conditions.

Have more confidence in your diagnosis with a spectrum of screens to assess aldosterone/cortisone ratio, plasma renin activity, and more.

Screen for rare genetic mutations including cystic fibrosis, Prader-Willi syndrome, and more for diagnostic insights that inform the path forward.

The power of Quest

    This information is provided for informational purposes only and is not intended as medical advice. A physician’s test selection and interpretation, diagnosis, and patient management decisions should be based on his/her education, clinical expertise, and assessment of the patient.



    1. American Thyroid Association. Prevalence and impact of thyroid disease. Accessed August 5, 2021.

    2. Garber JR, Cobin RH, Gharib H, et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr Pract. 2012;18(6):988-1028. doi:10.4158/EP12280.GL

    3. American Thyroid Association. 2016 American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis. Thyroid. 2016:26(10):1343-1423. doi:10.1089/thy.2016.0229

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