Skip to main content
Quest Diagnostics

Testing for Each Trimester

Prenatal care is part of a healthy pregnancy and outcome

Insights and support for every step along the pregnancy journey

Your patient’s pregnancy can be a busy time with lots of testing. Our interactive test menu and resources can help you recommend the right tests at the right time.

 

  RECOMMENDED LABORATORY SCREENING     CORRESPONDING QUEST TEST     TEST CODE  
OB Panel (can be ordered as a panel or individually)a Obstetric Panel 20210
OB Panel Individual components CBC (includes Differential and Platelets) 6399
  Antibody Screen, RBC with Reflex to Identification, Titer, and Antigen Typingb 795
  ABO Group and Rh Type 7788
  RPR (Diagnosis) with Reflex to Titer and Confirmatory Testingb (nontreponemal screening for syphilis) 36126
  Hepatitis B Surface Antigen with Reflex Confirmationb 498
  Rubella Immune Status 802
Obstetric Panel with Fourth Generation HIV Individual components This alternative panel is available and may be ordered to simultaneously screen for HIV infection, in addition to the tests above 93802
Additional OB Panel component HIV-1/2 Antigen and Antibodies, Fourth Generation, with Reflexesb 91431

Additional informative 1st trimester tests
Cervical cytology screening, if indicateda Image-Guided Pap with Age-Based Screening Protocolsa 91384
  Image-Guided Pap with Age-Based Screening with CT/NGa 91385
  Image-Guided Pap with Age-Based Screening with CT/NG, Trichomonasa 91386
  Pap alone See note belowa
Urinalysis Urinalysis, Macroscopic 6448
  Urinalysis with Reflex to Microscopic 7909
Zika Testing Zika Virus RNA, Qualitative, Real-Time RT-PCR 93870
  Zika Virus RNA, Qualitative, Real-Time RT-PCR Panel, Serum/Urine 94221
  Zika Virus RNA, Qualitative Real-Time, RT-PCR, Serum/Urine and IgM Panel 36758
  Although rates of Zika virus infection have decreased in the United States, obstetrician–gynecologists and other healthcare providers should continue to assess their patients for potential exposure based on travel or sexual history and test symptomatic patients with possible exposure and pregnant women with ongoing exposure regardless of symptoms in accordance with the Centers for Disease Control and Prevention recommendations.

One or both of the following screens for fetal aneuploidy should be offered during the 1st trimester
First Trimester Screen

First Trimester Screen, hCG

The screen includes PAPP-A (Pregnancy-associated Plasma Protein-A), hCG, Nuchal Translucency (NT) test; and risk assessments for trisomy 21 and trisomy 18

 16145
Maternal Serum Screen (Part 1)

Stepwise, Part 1

The screen includes PAPP-A (Pregnancy-associated Plasma Protein-A), hCG, Nuchal Translucency (NT); and risk assessments for trisomy 21 and trisomy 18

 16463
 

Serum Integrated Screen, Part 1

PAPP-A (Pregnancy-associated Plasma Protein-A)

 16165
 

Sequential Integrated Screen, Part 1

This screen includes PAPP-A (Pregnancy-associated Plasma Protein-A), hCG, Nuchal Translucency (NT), Down syndrome, and trisomy 18 risk and interpretation

 16131
 

Integrated Screen, Part 1

This screen includes PAPP-A (Pregnancy-associated Plasma Protein-A) and Nuchal Translucency (NT)

 16148
Noninvasive prenatal screening QNatal® Advanced 92777

Informative infectious disease 1st trimester tests
Tuberculosis (TB), if indicatedc QuantiFERON®-TB Gold Plus, 1 Tube 36970
  QuantiFERON®-TB Gold Plus, 4 Tubes, Draw Site Incubated 36971
  T-SPOT®.TB 37737
Chlamydiad Chlamydia trachomatis RNA, TMA, Urogenital 11361
Gonorrhea, if indicatedd Neisseria gonorrhoeae RNA, TMA, Urogenital 11362
Chlamydia and gonorrhea Chlamydia/Neisseria gonorrhoeae RNA, TMA, Urogenital 11363
HIV testing HIV-1/2 Antigen and Antibodies, Fourth Generation, with Reflexesb 91431
Hepatitis C testing Hepatitis C Antibody with Reflex to HCV, RNA, Quantitative, Real-Time PCRb 8472
  Hepatitis C Antibody with Reflex to HCV RNA,PCR w/Reflex to Genotype, LiPA 94345

2-RECOMMENDED LABORATORY SCREENING

CORRESPONDING QUEST TEST

TEST CODE

CBC

 CBC (includes Differential and Platelets) This screen includes WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (absolute and percent neutrophils, lymphocytes, monocytes, eosinophils, and basophils)

6399

 

 CBC (H/H, RBC, Indices, WBC, Plt) This screen includes WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count

1759
Gestational diabetes screening

Glucose Gestational Screen (50g), 135 Cutoff (ACOG supported 1st step of 2-step GDM evaluation)

8477

 

Glucose Gestational Screen (50g), 140 Cutoff (ACOG supported 1st step of 2-step GDM evaluation)

19833

 

 Glucose Tolerance Test, Gestational, 4 specimens (100g) (ACOG supported 2nd step of 2-step GCM valuation)

6745
One or more of the following should be offered as appropriate in the 2nd trimester
Quad Screene

Quad Screen
This screen includes AFP, unconjugated Estriol, hCG, Dimeric Inhibin A, and risk assessments for trisomy 21, trisomy 18, and ONTD

30294
Maternal Serum Screen (Part 2)

Serum Integrated Screen, Part 2 This screen includes AFP, hCG, uE3, and DIA

16167
Maternal Serum Alpha-Fetoprotein

Maternal Serum AFP

5059
Diagnostic Chromosomal Analysis via amniocentesis or chorionic villus sampling, if indicatede

Chromosome Analysis, Chorionic Villus Sample

14592

 

 Chromosome Analysis, Amniotic Fluidb

14590

2-RECOMMENDED LABORATORY SCREENING

CORRESPONDING QUEST TEST

TEST CODE
CBC

CBC (includes Differential and Platelets)
This screen includes WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count, MPV and Differential (absolute and percent neutrophils, lymphocytes, monocytes, eosinophils, and basophils)

6399

 

 CBC (H/H, RBC, Indices, WBC, Plt)
This screen includes WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelet Count

1759
D (Rh) antibody screen

Antibody Screen, RBC with Reflex to Identification, Titer, and Antigen Typinge

795
Group B streptococcal disease

Streptococcus Group B Culture

5617

 

 Streptococcus Group B with Susceptibility Culture

15090

 

 Streptococcus Group B DNA, PCR with Broth Enrichment

91768

 

 Streptococcus Group B DNA, PCR with Broth Enrichment and Reflex to Susceptibilitye

91770
Chlamydia (if patient tested positive or is high risk due to age or lifestyle)

Chlamydia trachomatis RNA, TMA, Urogenital

11361
Gonorrhea (if patient tested positive or high risk due to age or lifestyle)

Neisseria gonorrhoeae RNA, TMA, Urogenital

11362
Chlamydia and gonorrhea (if patient tested positive or high risk due to age or lifestyle)

Chlamydia/Neisseria gonorrhoeae
RNA, TMA, Urogenital

11363
RPR (if patient tested positive or high risk due to age or lifestyle) RPR (Diagnosis) with Reflex to Titer and Confirmatory Testinge 36126
HIV testing (if patient is high risk due to lifestyle) HIV-1/2 Antigen and Antibodies, Fourth Generation, with Reflexesb 91431

a The age-based offerings are based on ACOG recommendations and include image-guided Pap tests. Non-imaged Paps as well as conventional Paps are also available at Quest Diagnostics. Test codes may vary by location. Please contact your local laboratory or go to QuestDiagnostics.com/TestCenter for more information.

 

b Reflex testing may be performed at an additional charge.

 

c Risk factors include known HIV infection; close contact with individuals known or suspected to have TB; medical risk factors such as diabetes, lupus, cancer, alcoholism, and drug addiction; birth in or emigration from countries with high prevalence; being medically underserved; homelessness; living or working in long-term care facilities, such as correctional institutions, mental health institutions, and nursing homes.

 

d If positive, test-of-cure should be performed within 3-4 weeks post-treatment.

 

e If Antibody Screen is positive, Antibody Identification, Titer, and Antigen Typing will be performed at an additional charge. If RPR screen is reactive, RPR Titer and FTA Confirmatory testing will be performed at an additional charge. When only a single test, Hepatitis B Surface Antigen, is ordered to diagnose Hepatitis B in a pregnant woman, additional tests such as liver enzymes should be ordered to confirm the diagnosis.

 

Test codes may vary by location. Please contact your local laboratory for more information.

Click to download our pregnancy journey brochure

Click here
Genetic carrier screening

QHerit®, our innovative genetic carrier screening portfolio provides clinically relevant, right-sized panels that deliver information that you and your patients need to help plan their futures.

Click to learn more

Center of Excellence for fertility testing

ReproSource® empowers you to make the best decisions about patient fertility treatments, with access to a network of experts and high-quality testing.

Click to learn more

Genetic consultation available

Certified Genomic Science Specialists are available to help with test selection and results interpretation 1.866.GENE.INFO (1.866.436.3463)

Contact us

Contact us to receive additional information on our lab tests, services, and coverage

Contact us

Pregnant Patients

Test directory

With more than 3,500+ tests available, we can support every stage of a woman’s life with important insights

Learn more

Resources

We offer a variety of useful resources for healthcare professionals

View Resources

Patient info

For assistance with questions about the testing process or locations, call 1.866.MYQUEST (1.866.697.8378)

Our company

Quest® is the brand name used for services offered by Quest Diagnostics Incorporated and its affiliated companies. Quest Diagnostics Incorporated and certain affiliates are CLIA-certified laboratories that provide HIPAA-covered services.  Other affiliates operated under the Quest® brand, such as Quest Consumer Inc., do not provide HIPAA-covered services. 

 

Quest®, Quest Diagnostics®, any associated logos, and all associated Quest Diagnostics registered or unregistered trademarks are the property of Quest Diagnostics. All third-party marks—® and ™—are the property of their respective owners. © 2025 Quest Diagnostics Incorporated. All rights reserved. Image content features models and is intended for illustrative purposes only.