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QNatal® Advanced 
noninvasive prenatal
screening


Empowering better access to important prenatal screening

 

QNatal® Advanced is a noninvasive cell-free DNA (cfDNA) prenatal screen that screens for the most common fetal aneuploidies, including Down syndrome. In addition, if elected, QNatal Advanced can screen for certain microdeletions and/or fetal sex. Test code 92777

While many may offer prenatal screening, we deliver on the promise of making advanced screening more accessible.
 

Prenatal screening should be available to all. 
79% of patients pay less than $99.a

Access made easy

We make QNatal Advanced testing more accessible with cost transparency, financial tools, and support at every step. It starts by being in-network with the majority of health plans nationwide.

 

For the insured—with coverage and appropriate ICD-10 diagnosis codes, patients can pay as little as $0 based on their insurance plan
For the insured who experience a denial—if the health plan denies QNatal Advanced as a “noncovered service,” the patient should pay no more than $299
For the uninsured—uninsured patient price (UPP)b available in all states for qualified patients

Helping provide patients better peace of mindc

QNatal® Advanced is a noninvasive cell-free DNA (cfDNA) prenatal screen that screens for the most common fetal aneuploidies, including Down syndrome. In addition, if elected, QNatal Advanced can screen for certain microdeletions and/or fetal sex. Test code 92777

High-quality prenatal screening


Comprehensive screening, easy-to-read results



Access to advanced screening and accurate results from a single source.c

That’s our promise to you and your patients.


Click for more information and to order QNatal Advanced

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a Based on Quest Diagnostics 2022 fiscal year claims analysis.

 

b Alternative UPP pricing is available in Florida, New Hampshire, Massachusetts, Maine, Rhode Island, Vermont, and Texas.

 

c QNatal® Advanced is a cell-free DNA test that screens for increased risk of certain fetal chromosomal abnormalities that may cause birth defects, including Trisomy 21 (Down Syndrome), Trisomy 18, Trisomy 13, and certain sex chromosome abnormalities (ie, 45,X, 47,XXY, 47,XXX, and 47,XYY). In addition, if selected as an option, QNatal Advanced can screen for certain microdeletions (ie, 22q, 5p, 1p36, 15q, 11q, 8q, and 4p) that may cause birth defects, and/or for fetal sex. This test does not assess the risk of fetal anomalies such as neural tube defects or ventral wall defects. QNatal Advanced is not recommended before 10 weeks gestation due to a significantly increased risk of a failed result.

 

QNatal is a “screening” test, not a diagnostic test, and therefore all positive/increased risk results should be followed by genetic counseling and further diagnostic testing and procedures, when clinically indicated. Pregnancy management decisions should not be based on the results of a
cfDNA test alone. As with any test, there may be false positives or false negatives. The positive predictive value of the screening test varies by genetic marker, and may be lower for rare conditions. Performance data for QNatal Advanced may be obtained by contacting Quest Diagnostics at
1.866.GENE.INFO (1.866.436.3463).

 

QNatal Advanced is a laboratory-developed test that has been developed and validated, pursuant to the Clinical Laboratory Improvements Amendments of 1988 (CLIA), and as such it has not been reviewed by FDA.

 

Reference:

  1. Guy C, Haji-Sheikhi F, Rowland CM, et al. Prenatal cell-free DNA screening for fetal aneuploidy in pregnant women at average or high risk: Results from a large US clinical laboratory. Mol Genet Genomic Med. 2019;7(3):e545. doi:10.1002/mgg3.545 (finding a no-call rate of 3.5%; several authors affiliated with Quest Diagnostics). “No call rate” refers to the percentage of samples for which results could not be reported.
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Genomic science specialists are available to help with test selection and results interpretation 1.866.GENE.INFO (1.866.436.3463)

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