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Introduction

Get to know Dr. Fesko

Hear from Dr. Fesko about his role at Quest, his prior experience, and more.

FAQ: Learn more about Dr. Fesko

Dr. Fesko: "My work as a practicing oncologist showed me how powerful diagnostics can be in shaping a patient's journey. I realized early on that every treatment decision begins with the right diagnosis, and the more precise we can be, the better the outcomes. That's been my guiding focus ever since."

Dr. Fesko: "It's central. Having been directly involved in patient care, I understand the clinical challenges physicians face daily. This perspective helps me ensure that Quest's diagnostics are not only innovative but also practical and impactful in real-world clinical settings."

Dr. Fesko: "I think we're on the verge of transformative applications of real-world evidence (RWE), particularly in oncology. The ability to integrate patient data from varied sources and apply it to treatment decisions could really change the way we approach individualized care."

Dr. Fesko: "I'm an activate participant in the field, attending conferences and engaging with the latest research. I also value the continous collaboration with Quest's research and development teams, where we explore new technologies and innovations that shape the future of diagnostics."

Dr. Fesko: "Despite my demanding schedule, I always make time to disconnect and explore the outdoors with my family. We love visiting national parks, and it's a great way to recharge while spending time together."

Read Dr. Fesko's white paper

Oncology Center of Excellence White paper

The evolving role of diagnostic labs in oncology: Navigating biomarker-driven therapies

The escalating global challenge of oncology care demands new approaches to detection, diagnosis, and treatment. 

 

This white paper is free and can be downloaded and read at your convenience.

PCR processing of samples in a 96 well plate at a biotechnology lab

Ask Dr. Fesko a Question

Curious about emerging trends in oncology diagnostics? Wondering how companion diagnostics could support your clinical trial? Submit your question to Dr. Fesko, and he'll respond with insights based on his extensive expertise in precision medicine and clinical practice.

Responses provided within 48 hours. Your questions will be answered directly and privately. Some frequently asked questions may also be shared on this page with your permission, adding to our "Insights from Dr. Fesko" section.

Submit your question

Key Skills & Areas of Expertise

Clinical Oncology Practice

  • Over 20 years as a practicing oncologist specializing in hematology and oncology
  • Deep familiarity with patient care, treatment protocols, and the challenges faced in clinical settings

Precision Medicine & Companion Diagnostics

  • Pioneered the development of advanced diagnostics like Quest's 500-gene somatic tumor panel
  • Expertise in tailoring diagnostic solutions to enable personalized treatment pathways

Medical Affairs Leadership

  • Leads medical strategies, clinical development, and internal analytics at Quest Diagnostics
  • Collaborates across multiple functional areas including Regulatory FDA, HE0R, and R&D

Decentralized Clinical Trials

  • Instrumental in developing Quest's decentralized clinical trials model to improve patient access and engagement
  • Focused on integrating real-world evidence to enhance trial effectiveness

Thought Leadership & Education

  • Published author of numerous peer-reviewed publications
  • Sought-after speaker at premier healthcare conferences like Clinical Biomarkers & World CDx and the Precision Medicine World Conference

Cross-functional Collaboration

  • Experienced in working with diverse teams to bring diagnostics from concept to clinical use
  • Board member of the UPMC Laboratory joint venture with Quest Diagnostics, fostering partnerships that advance healthcare

Patient-centric Innovation

  • Committed to making diagnostics more accessible and affordable
  • Advocates for diagnostics that genuinely impact patient outcomes and experiences

Bio

Dr. Yuri Fesko, Chief Medical Officer at Quest Diagnostics, combines his experience as a practicing oncologist with a strategic focus on advancing diagnostics. With deep expertise in oncology, hematology, and internal medicine, Dr. Fesko brings a clinician's insight to Quest's medical affairs and clinical development, championing innovations like the 500-gene somatic tumor panel and decentralized trial models.

Born and raised in New York City, Dr. Fesko remains closely connected to his community, where he and his wife reside. Outside of work, he's an avid hiker and enjoys exploring national parks with his family. Known for his collaborative spirit, Dr. Fesko believes that each patient deserves diagnostics that drive better outcomes — and he's dedicated to making that vision a reality.