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Tap into the power of Quest

Specialists like rheumatologists and gastroenterologists support patients facing a vast array of overlapping symptoms. For confident diagnosis, you need the right test, at the right time. At Quest, our specialized testing, tailored solutions, and patient accessibility also help specialists like you collaborate to solve your most challenging cases – especially when they overlap. 


Discover our full menu of specialized tests:

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Clinical indication


Featured test or panels

Rheumatoid arthritis, antiphospholipid syndrome (APS), Sjögren syndrome, systemic sclerosis, polymyositis, lupus, mixed connective tissue disease (MCTD),  AI thyroid diseases

Screens for 8 of the most common AI conditions, helps to diagnose complex cases with overlapping symptoms.

ANAlyzeR™ ANA IFA with reflex to Titer/Pattern, Systemic AI

Single biomarker components also available separately


Aids in diagnosis of more autoimmune myopathies than most standard panels. Includes HMGCR + cN-1A. Single biomarker components also available a la carte.

Extended Myositis Specific Antibody (MSA) Panel

Single biomarker components also available separately.


Interstitial lung disease (ILD)

Offers simultaneous testing of biomarkers associated with autoimmune disorders (including connective tissue disorders) that may be an underlying cause for ILD.

Interstitial Lung Disease (ILD) Panel

Single biomarker components also available separately.


Curated panels or single biomarker menu to diagnose and monitor lupus.

C1q Anitbody (IgG),

Complement Component C3 C4 C5 Ch50

SLE disease activity panel

Rheumatoid arthritis

Enables early diagnosis, helps identify patients who will develop RA in the future, and predicts risk of more severe RA.


Sjögren syndrome

Uses novel markers associated with early Sjögren’s syndrome

Early Sjögren Syndrome Panel 

Systemic sclerosis (SSc)

SSc-specific antibodies enable early diagnosis of  patients with non-specific symptoms

Systemic Sclerosis 12 Antibodies Panel 2

Therapeutic drug monitoring

Supports biologic therapy prescription and monitoring with drug level and anti-drug antibody testing as a panel or individual components

Adalimumab Rheum, Infliximab Rheum

Ankylosing spondylitis

Supports differential arthritis diagnosis

HLA-B27 Antigen

Gout treatment planning

Assesses likelihood of severe cutaneous adverse reactions (SCAR) in response to the drug Allopurinol

HLA-B*58:01 Genotype


Clinical Indication


Featured Tests or Panels


30+ specialty tests to support IBD care from differential diagnosis, disease monitoring, and treatment monitoring. 

detailed below


Differential diagnosis

Calprotectin, stool

Inflammatory Bowel Disease Differentiation Panel


Disease monitoring

Calprotectin, stool

Lactoferrin Qualitative


Therapeutic Drug Monitoring

Level + anti-drug:

Adalimumab Gastro

Infliximab Gastro

Ustekinumab: Limited access code: ask your Quest representative for more information 

Vedolizumab: Limited access code: ask your Quest representative for more information 


TPMT activity

TPMT genotype



Exocrine pancreatic insufficiency

Supports differential diagnosis (eg, from IBS, IBD, celiac), and disease monitoring

Pancreatic Elastase

Autoimmune hepatitis

Helps differentiate autoimmune hepatitis type 1 vs. type 2, and other types of hepatitis and primary biliary cholangitis (PBC)

Actin Antibody (Smooth Muscle)

Liver Kidney Microsomal (LKM-1) antibody(IgG)

Mitochondrial Antibody (AMA) with reflex to Titer


Antibody and genetic testing to support diagnosis and monitoring

Celiac Disease panels:



Single components also available separately.


Genetic tests:

HLA Typing for Celiac Disease

HLA-DQA1 Low Resolution Typing

HLA-DQB1 Low Resolution Typing



Let Quest enable more coordinated care between your autoimmune specialty teams

Optimizing autoimmune care teams starts with having 1 shared diagnostics partner. Quest supports specialists in coordinating care by providing insights and data on diagnostic trends, creating a more comprehensive view into patients' health so that you and your peers can guide them to a better future. 

Go beyond our testing portfolio and you'll find expertise and intuitive experiences that optimize diagnostics.

Celiac or IBD? Gut-check with Quest

Celiac disease and IBD share many signs and symptoms.Testing for both conditions can help patients with vague or overlapping symptoms connect to the right treatment faster. Download our IBD guide to learn more about our broad menu including antibody and genetic testing. 


Get the guide

Innovative tests that cut through complexity  

Because no single test provides results for definitive diagnosis for rheumatic disease, Quest helps cut through complexity of overlapping and varied symptoms with comprehensive panels or single biomarker tests.  



See the portfolio

Your Quest consult is always a phone call away. 

Set up a call today to learn more about how 1 comprehensive lab provider can streamline patient care and your operations.
Quest employee and HCP having conversation

Quest has solutions across the entire autoimmune care continuum to support:


- Screening or evaluation panels

- Specialty testing

Risk Stratification

- Pre-biologic panels

Treatment planning

- Therapeutic response



Make informed, efficient decisions about your patients’ care with Quest



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