Brazil Nut Whole Allergen

Test code 2818

Hidden allergen often found in cookies, insect repellent, and beauty products.1

  • Extensive cross-reactivity within the family can be expected2
  • Generally persists and is potentially life-threatening3

Ber e1

Associated with systemic reactions4

  • Storage protein (2s albumin)1
  • Resistant to digestion by pepsin, and a major allergen1
  • Very stable to gastric digestion1
  • Major allergen in Brazil nuts1

Positive 2818 with negative Ber e1 results may be explained by sensitization to5

  • Other Brazil nut storage proteins or lipid transfer protein (LTP)
  • Pollen proteins like profilin or PR-10 proteins
  • CCD (cross-reacting carbohydrate determinants)

As in all diagnostic testing, a diagnosis must be made by the physician based on test results, individual patient history, the physician’s knowledge of the patient, and the physician’s clinical judgement.

Get more information

For more information, contact your local Sales Representative.

 

For clinical information and specimen requirements,
visit the test center.

 

Download the Tree Nut Allergen Component Testing brochure.

References

1. www.phadia.com/en/Products/Allergy-testing-products/ImmunoCAP-Allergen-Information/Food-of-Plant-Origin/Seeds--Nuts/Brazil-nut-/

2. Yman L. Botanical relations and immunological cross-reactions in pollen allergy. 2nd ed. Pharmacia Diagnostics AB. Uppsala, Sweden. 1982: ISBN 91-970475-09.

3. Bartolome B, Mendez JD, Armentia A, Vallverdu A, Palacios R. Allergens from Brazil nut: immunochemical characterization. Allergol Immunopathol (Madr) 1997;25(3):135-144.

4. Sicherer SH, Sampson HA. Peanut and tree nut allergy. Curr Opin Pediatr 2000;12(6):567-573.

5. www.phadia.com