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Respiratory Allergy Profile

Respiratory Allergy Profile

Test Highlight

Respiratory Allergy Profile


Clinical Use

  • Diagnose suspected IgE antibody-mediated respiratory reactions

Clinical Background

The ImmunoCAP® Respiratory Allergy Profile provides an accurate and convenient method of confirming or excluding atopy in patients with symptoms that might be attributed to allergy.1 In the United States, allergic rhinitis is the most common cause of rhinitis, affecting up to 40% of children and 10% to 30% of adults.2 These cases require different treatment than that used for non-allergic rhinitis. Furthermore, allergy testing helps identify allergy-triggered asthma that is present in 60% to 90% of children and 50% of adults with asthma.3 Treating the allergy is often beneficial in these cases. Thus, allergy testing results can be helpful when making treatment decisions.

Because different types of allergens are found in different parts of the country, Quest Diagnostics offers Regional Profiles that focus on allergens specific to individual regions (Table). For example, region XIV covers the California central valley area. By using the appropriate Regional Profile, your patients’ test results reflect the allergen exposure from a particular geographic location.

Table. Quest Diagnostics Regional Respiratory Allergy Profiles
Test Code Profile Region Covered
10643 I CT, MA, ME, NH, NJ, NY, PA, RI, VT
10644 II DC, DE, MD, NC, VA
10285 III GA, FL (North), SC
10286 IV FL (South of Orlando)
10646 V IN, KY, OH, TN, WV
10647 VI AL, AR, LA, MS
10648 VII MI, MN, WI
10649 VIII IA, IL, MO
10650 IX KS, NE, ND, SD
10651 X OK, TX
10653 XI AZ (Mountains), CO, ID (Mountains), MT, NM, UT, WY
10654 XII AZ (South), CA (Southeast Desert)
10655 XIII CA (Southern Coast)
10668 XIV CA (Central Valley)
10669 XV ID (South), NV
10657 XVI OR, WA (Central and East)
10658 XVII CA (Northwest), OR (West), WA
10673 XVIII Alaska
38828 XIX Puerto Rico


Each regional profile includes total IgE; the most common ImmunoCAP specific IgE allergens for all regions; and the most common ImmunoCAP specific IgE allergens for the particular region.


  1. American Academy of Allergy, Asthma, and Immunology. AAAAI Work Group Report: Allergy diagnosis in clinical practice. November 2006. Available at: www.aaaai.org. Accessed January 29, 2013.

  2. Dykewicz MS, Fineman S. Executive summary of joint task force practice parameters on diagnosis and management of rhinitis. Am Allergy Asthma Immunol. 1998;81:463-468.

  3. Li JT, Pearlman DS, Nicklas RA, et al. Algorithm for the diagnosis and management of asthma: a practice parameter update. Am Allergy Asthma Immunol. 1998;81:415-420.

Content reviewed 04/2013

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* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.