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Beta-Amyloid 42/40 Ratio and Apolipoprotein E (APOE) Isoform Panel, CSF
To view specimen requirements and codes please Select a regional laboratory.Not sure which laboratory serves your office? Call us 866-MYQUEST (866-697-8378)
82542 (x2), 82172
**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
See Laboratory Report
This test for CSF Beta-Amyloid and CSF/Serum Apolipoprotein E by LC-MS/MS monitors both CSF beta-amyloid 40 (AB40) and 42 (AB42) endogenous peptides, rather than only AB42. Total ApoE and ApoE isoform analysis, in conjunction with the AB42/40 ratio, can aid in assesing disease. The quantitation of both AB peptides permits the normalization of beta amyloid levels circulating in cerbrospinal fluid in different patients by using a ratio of beta-amyloid 42/beta amyloid 40, resulting in an improved sensitivity for monitoring cognitive impairment that can progress to Alzheimer's disease.
ApoE3,Alzheimer's Disease (AD),ABeta 42,AB40,ApoE4,ABeta 40,AB42,ApoE2
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
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