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Test Name

Paraneoplastic Antibody Evaluation with Reflex to Titer and WB, Basic, CSF

CPT Code(s)

86255 (x10), 86341

Includes

If the Paraneoplastic Ab Screen, IFA is positive for Aquaporin-4 Ab, IFA, then Aquaporin-4 (AQP4) Antibody (IgG), CBA, CSF will be performed at an additional charge (CPT code(s) 86255).
If Aquaporin-4 (AQP4) Antibody (IgG), CBA result is positive, then a titer will be performed at an additional charge (CPT code(s) 86256) .
If the Paraneoplastic Ab Screen, IFA is positive for ANNA3 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256) .
If the Paraneoplastic Ab Screen, IFA is positive for PCA2 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If the Paraneoplastic Ab Screen, IFA is indeterminate or positive for ANNA1, ANNA2, PCA1, PCA-Tr (DNER), Amphiphysin, GAD65, or CRMP5 (CV2) antibodies, then Paraneoplastic Ab, western line blot will be performed at an additional charge (CPT code(s) 84182 x7, 86341).
If the Paraneoplastic Ab Screen, IFA is positive for NMDAR1, LGI-1, CASPR2, AMPAR1, AMPAR2, GABA receptor B, or Voltage Gated Antibodies, then Paraneoplastic Antibody, CBA IFA will be performed at an additional charge (CPT code(s) 86255 x6).
If Paraneoplastic Antibody, CBA IFA is positive for NMDAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for AMPAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA, IFA is positive for AMPAR2 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for GABA receptor B Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for LGI-1 Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If Paraneoplastic Antibody, CBA IFA is positive for CASPR2 Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256).
If the Paraneoplastic Ab Screen, IFA is positive for LGI-1, CASPR2, or Voltage Gated Antibodies, then Voltage-Gated Potassium Channel (VGKC) Antibody, CSF will be performed at an additional charge (CPT code(s) 83519).

Reference Range(s)

See Laboratory Report

Clinical Significance

Fluorescent staining patterns on multiple neuronal and non-neuronal tissues identify likely autoantibodies present. Reflex testing to western line blot, cell based indirect immunofluorescent assay or radioimmunoassay may define specific autoantibodies.

Alternative Name(s)

Brain antibody,Anti-neuronal antibody

To view specimen requirements and codes please Select a regional laboratory.

Not sure which laboratory serves your office? Call us 866-MYQUEST (866-697-8378)

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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Paraneoplastic Antibody Evaluation with Reflex to Titer and WB, Basic, CSF
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