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Test Name

Drug Monitoring, Antipsychotics, with Confirmation, Serum

To view specimen requirements and codes please Select a regional laboratory.

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CPT Code(s)**

80307
**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.

Includes

Aripiprazole, Chlorpromazine, Clozapine, Fluphenazine, Haloperidol, Loxapine, Mesoridazine, Molindone, Olanzapine, Quetiapine, Risperidone, Thioridazine, Thiothixene, Trifluoperazine, Ziprasidone

If screening drug class result is equal to or greater than the cutoff, then confirmation testing will be performed at an additional charge (CPT code(s): 80342 or 80343 or 80344).

Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference Range(s)

See Laboratory Report

Clinical Significance

Antipsychotic (AP) drugs are widely prescribed for the treatment of schizophrenia and psychosis. The so-called first generation or typical APs were developed in the 1950s and show severe side-effects such as extrapyramidal symptoms due to their pharmacological action on d2 and d4 receptors. As a measure of reducing these severe side-effects, a range of ‘second generation’ APs were developed. These newer generation drugs act considerably less on d2 and d4 receptors and therefore exhibit less extrapyramidal side-effects.
Over the last decade, the prescription rate of APs (more notably second generation) has increased worldwide, [1-3] especially among young adults and children [1-4]. However, second generation APs are not entirely free of side-effects. Irrespective of their generation, it has been shown that these drugs can increase the risk of sudden cardiac death with studies showing that the risk of sudden cardiac death is increased threefold among patients treated with APs.

Test FAQ

Pain Management Antipsychotics, With Confirmation, Serum and Urine

Alternative Name(s)

Prescription Drug Monitoring,Pain Management

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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Drug Monitoring, Antipsychotics, with Confirmation, Serum
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