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Test Name

IBSDetex™ (New)

CPT Code(s)

83520 (x2)

Includes

Cytolethal Distending Toxin B Antibody and Vinculin Antibody

Methodology

Enzyme Linked Immunosorbent Immunoassay (ELISA)

Reference Range(s)

See Laboratory Report

Clinical Significance

Recent reports suggest that elevated anti-Cytolethal distending toxin B (CdtB) and anti-Vinculin antibody levels are more commonly found in patients with diarrhea predominant irritable bowel syndrome (IBS) than in healthy controls. These same reports found that patients with other bowel diseases and a subset of healthy patients may also have elevated levels of anti-CdtB anti-Vinculin. Patients with celiac disease, in particular, were found to commonly have elevated anti-CdtB levels. Moreover, a positive anti-CdtB and/or anti-Vinculin antibody does not exclude inflammatory bowel disease or another diagnosis. Results should be considered in the context of the overall medical evaluation.

Alternative Name(s)

Inflammatory Bowel Syndrome,CdtB antibody,Irritable Bowel Syndrome test,anti-CdtB,anti-Vinculin,IBS Test

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Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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IBSDetex™
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