Test Center

My Recent Searches

  • No Recent Search.

My Tests Viewed

  • No Test Viewed.
Test Name

Voriconazole

To view specimen requirements and codes please Select a regional laboratory.

Not sure which laboratory serves your office? Call us 866-MYQUEST (866-697-8378)

CPT Code(s)**

80299
**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.

Methodology

Chromatography/Mass Spectrometry

Reference Range(s)

Steady state trough levels are achieved within 1 day when an IV loading dose is used and after approximately 5 days of oral or IV therapy without a loading dose.

Therapeutic range
Prophylaxis: trough >0.5 mcg/mL
Therapeutic range for treatment: trough 2.0-5.5 mcg/mL

Serum trough levels less than or equal to 1 mcg/mL are reported to be associated with lack of therapeutic response and serum trough levels >5.5 mcg/mL have been reported to be associated with reversible neurological adverse events and hepatotoxicity.

Co-administration of drugs that metabolically induce or inhibit CYP2C19, or other conditions that affect CYP2C19 may alter voriconazole metabolism.

Clinical Significance

The antifungal drug voriconazole is commonly used in the treatment of various types of fungal infections. An increased fungal resistance to similar drugs of greater toxicity has promoted the use of voriconazole in treating infections caused by aspergillus and other fungal species. The chronic nature of fungal infections demands constant monitoring of voriconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

94096
94096
94096
94096
94096
94096
94096X
94096X
94096
94096
94096
94096
94096X
94096
94096 NTC
94096 VORI
VORI LC MS MS
94096
94096
94096
94096
94096
94096
94096
94096
Voriconazole
94096