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Test Name

NAFLD Fibrosis Score

CPT Code(s)

82947, 84450, 84460, 85049, 82040

Includes

Glucose, AST, ALT, Platelet Count, Albumin, Calculated Components, Personal Factors

Methodology

Spectrophotometry (SP) • Electronic Sizing and Counting/Cytometry/Microscopy

Reference Range(s)

See individual tests

Clinical Significance

The NAFLD fibrosis score is a simple noninvasive approach to identify patients that may have significant liver fibrosis and who therefore might benefit from additional studies such as elastography or liver biopsy. Non-alcoholic fatty liver disease (NAFLD) affects approximately 30% of adults in developed countries. It is associated with obesity, diabetes, and dyslipidemia and is considered the liver manifestation of the metabolic syndrome. This disease is often asymptomatic. In some individuals, NAFLD is associated with inflammation (non-alcoholic steatohepatitis [NASH]) and may progress to liver fibrosis and ultimately to cirrhosis and attendant complications. Such individuals are also at risk for the development of hepatocellular carcinoma. In patients with NAFLD, liver fibrosis is an important prognostic factor that predicts progression and outcome. The NAFLD fibrosis score was initially published by Angulo et al. (Hepatology 45, 846 (2007)) and has since been extensively validated. The score assesses selected laboratory measures (glucose levels, platelet count, albumin, AST/ALT ratio) in combination with basic patient characteristics (age and BMI). The panel components and the NAFLD fibrosis score are recommended by professional societies including AASLD, AGA and ACG.

Test FAQ

NAFLD Fibrosis Score

To view specimen requirements and codes please Select a regional laboratory.

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Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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NAFLD Fibrosis Score
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