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Test Name

Hydrocodone and Metabolite, Serum

CPT Code(s)

82646

Includes

Hydrocodone, Free and Hydromorphone, Free

Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference Range(s)

Hydrocodone, Free 5.0-24.0 ng/mL
Hydromorphone, Free 5.0-30.0 ng/mL

Clinical Significance

Therapeutic drug monitoring and confirmation of screen-positive results. Hydrocodone is an active component of Vicodin®, Lorcet®, Lortab®, etc. Serum half-life is 3.4 to 8.8 hours. Hydromorphone is an active ingredient in Dilaudid®. Serum half-life is 1.5 to 3.8 hours.

To view specimen requirements and codes please Select a regional laboratory.

Not sure which laboratory serves your office? Call us 866-MYQUEST (866-697-8378)

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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Hydrocodone and Metabolite, Serum
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