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Test Name

Alanine Aminotransferase (ALT)

CPT Code(s)

84460

Methodology

Spectrophotometry (SP)

Limitations

Trauma to striated muscle, tissue, rhabdomyolysis, polymyositis, and dermatomyositis may produce increased results. Hemolyzed samples may yield elevated results. Some illegal drugs (cocaine, anabolic steroids, ecstasy) may also produce increased results.

Reference Range(s)

  Male (U/L) Female (U/L)
<1 Month 3-25 3-25
1-11 Months 4-35 3-30
1-3 Years 5-30 5-30
4-12 Years 8-30 8-24
13-15 Years 7-32 6-19
16-19 Years 8-46 5-32
≥20 Years 9-46 6-29

Clinical Significance

Alanine Aminotransferase (ALT) measurements are particularly useful in the diagnosis and management of certain liver diseases, e.g., viral hepatitis and cirrhosis. ALT activity in tissue is generally much lower than aspartate aminotransferase (AST) activity and is found in highest concentrations in the liver. Significant elevations of ALT occur only in diseases of the liver. ALT is often measured in conjunction with AST to determine whether the source of the AST is the liver or the heart. ALT is normally not elevated in cases of myocardial infarction, i.e., a normal ALT, in conjunction with an elevated AST, tends to suggest cardiac disease. However, slight elevations of ALT may occur if an infarct destroys a very large volume of heart muscle.

Alternative Name(s)

SGPT,ALT

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Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

823
823
823
823
823
17426R
823X
823
823
17426R
823X
17426R
823
1347
823
823
823
3192
823X
6420
823
823
Alanine Aminotransferase (ALT)
823