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Test Name

Protein, Total and Albumin

CPT Code(s)

82040, 84155

Includes

Total Protein, Albumin, Globulin (calculated), Albumin/Globulin Ratio (calculated)

Methodology

See individual tests

Reference Range(s)

Protein, Total, Serum
  Male (g/dL) Female (g/dL)
<1 Month 4.1-6.3 4.2-6.2
1-5 Months 4.7-6.7 4.4-6.6
6-11 Months 5.5-7.0 5.6-7.9
1-19 Years 6.3-8.2 6.3-8.2
≥20 Years 6.1-8.1 6.1-8.1
Albumin 3.6-5.1 3.6-5.1
Globulin Male Female
  g/dL (calc) g/dL (calc)
<6 Months 1.3-2.4 1.3-2.1
6-11 Months 1.7-3.0 1.2-2.4
1-19 Years 2.1-3.5 2.0-3.8
≥20 Years 1.9-3.7 1.9-3.7
Albumin/Globulin Ratio 1.0-2.5 (calc)

Clinical Significance

The major proteins seen in the serum are albumin and globulin-the latter being primarily alpha 1 and alpha 2 globulin, beta globulin and gamma globulin. Albumin accounts for more than 50% of the total serum proteins. The albumin to globulin (A/G) ratio has been used as an index of disease state, however, it is not a specific marker for disease because it does not indicate which specific proteins are altered. The normal A/G ratio is 0.8-2.0. The A/G ratio can be decreased in response to a low albumin or to elevated globulins. Total globulins may be increased in some chronic inflammatory diseases (TB, syphilis) multiple myeloma, collagen disease, and rheumatoid arthritis.  Decreased levels are seen in hepatic dysfunction, renal disease and various neoplasms.

Alternative Name(s)

Globulin

To view specimen requirements and codes please Select a regional laboratory.

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Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

3293A
7577X
7577
7577
7577
7577
3293A
7577
9159T
3293A
7577X
30062
7577
7577
7577
7577
7577
2382
7577
7577
7577
9159T
3293A
3293A
7577X
17756
7577X
7577
85683
6295
7577
Protein, Total and Albumin
7577