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Test Name

Iron, Total and Total Iron Binding Capacity

CPT Code(s)

83540, 83550

Includes

Total Iron, Iron Binding Capacity, % Saturation (calculated)

Methodology

Spectrophotometry (SP)

Reference Range(s)

Iron,Total Male (mcg/dL) Female (mcg/dL)
<1 Month 32-112 29-127
1-11 Months 27-109 25-126
1-3 Years 29-91 25-101
4-19 Years 27-164 27-164
20-29 Years 50-195  
≥30 Years 50-180  
20-49 Years   40-190
≥50 Years   45-160 

Iron Binding Capacity

  Male (mcg/dL) Female (mcg/dL)
<1 Month 94-232 94-236
1-5 Months 116-322 89-311
6-11 Months 176-384 138-365
1-19 Years 271-448 271-448
≥20 Years 250-425 250-450

% Saturation Male Female
<1 Year Not established Not established
1-12 Years 8-48 % 8-45 %
13-19 Years 9-52 % 8-45 %
≥20 Years 15-60 % 11-50 %

Clinical Significance

Serum iron quantification is useful in confirming the diagnosis of iron-deficiency anemia or hemochromatosis. The measurement of total iron binding in the same specimen may facilitate the clinician's ability to distinguish between low serum iron levels caused by iron deficiency from those related to inflammatory neoplastic disorders. The assay for iron measures the amount of iron which is bound to transferrin. The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferrin concentrations but expressed as an iron measurement. To obtain the percent saturation, the serum iron is divided by the TIBC which gives the actual amount of saturated transferrin. The percent saturation is low in iron deficiency and high in iron storage diseases.

To view specimen requirements and codes please Select a regional laboratory.

Not sure which laboratory serves your office? Call us 866-MYQUEST (866-697-8378)

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

356F
7573X
7573
7573
7573
7573
356F
7573
356F
7573X
30133
7573
7573
7573
7573X
7573
7573
7573
7573
7573
7573
356F
7573X
356F
7573
7573X
7573
9070
6290
7573
Iron, Total and Total Iron Binding Capacity
7573