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Test Name

Prolactin

To view specimen requirements and codes please Select a regional laboratory.

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CPT Code(s)**

84146
**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.

Methodology

Immunoassay (IA)

Reference Range(s)

Adult Male 2.0-18.0 ng/mL
Adult Female    
  Non-Pregnant 3.0-30.0 ng/mL
  Pregnant 10.0-209.0 ng/mL
  Postmenopausal 2.0-20.0 ng/mL

Stages of Puberty (Tanner Stages)
  Female Observed Male Observed
  Stage I 3.6.12.0 ng/mL ≤10.0 ng/mL
  Stage II-III 2.6-18.0 ng/mL ≤6.1 ng/mL
  Stage IV-V 3.2-20.0 ng/mL 2.8-11.0 ng/mL

Clinical Significance

During pregnancy and postpartum lactation, serum prolactin can increase 10- to 20-fold. Exercise, stress, and sleep also cause transient increases in prolactin levels. Consistently elevated serum prolactin levels (>30 ng/mL), in the absence of pregnancy and postpartum lactation, are indicative of hyperprolactinemia. Hypersecretion of prolactin can be caused by pituitary adenomas, hypothalamic disease, breast or chest wall stimulation, renal failure or hypothyroidism. A number of drugs, including many antidepressants, are also common causes of abnormally elevated prolactin levels. Hyperprolactinemia often results in galactorrhea, amenorrhea, and infertility in females, and in impotence and hypogonadism in males. Renal failure, hypothyroidism, and prolactin-secreting pituitary adenomas are also common causes of abnormally elevated prolactin levels.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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Prolactin
746