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Test Name

Cardiolipin Antibodies (IgA, IgG, IgM)

CPT Code(s)

86147 (x3)

Methodology

Immunoassay (IA)

Reference Range(s)

Cardiolipin Antibody (IgA)

≤11 APL Negative
12-20 APL Indeterminate
21-80 APL Low to medium positive
>80 APL High positive
Cardiolipin Antibody (IgG)
≤14 GPL Negative
15-20 GPL Indeterminate
21-80 GPL Low to medium positive
>80 GPL High positive
Cardiolipin Antibody (IgM)
≤12 MPL Negative
13-20 MPL Indeterminate
21-80 MPL Low to medium positive
>80 MPL High positive

Clinical Significance

Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly systemic lupus erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.

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Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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Cardiolipin Antibodies (IgA, IgG, IgM)
7352