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Test Name

FSH and LH

To view specimen requirements and codes please Select a regional laboratory.

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CPT Code(s)**

83001, 83002
**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.

Methodology

Immunoassay (IA)

Reference Range(s)

FSH

Male 1.6-8.0 mIU/mL
Female    
  Follicular Phase 2.5-10.2 mIU/mL
  Mid-Cycle Peak 3.1-17.7 mIU/mL
  Luteal Phase 1.5- 9.1 mIU/mL
  Postmenopausal   23.0-116.3  mIU/mL
Children (<18 years old): FSH reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, the Quest Diagnostics FSH, Pediatrics assay is recommended (test code 36087).

LH
Male    
18-59 Years 1.5-9.3 mIU/mL
≥60 Years 1.6-15.2 mIU/mL
Female    
  Follicular Phase 1.9-12.5 mIU/mL
  Mid-Cycle Peak 8.7-76.3 mIU/mL
  Luteal Phase 0.5-16.9 mIU/mL
  Postmenopausal 10.0-54.7 mIU/mL
Children (<18 years old): LH reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, the Quest Diagnostics LH, Pediatrics assay is recommended (test code 36086).

Clinical Significance

FSH and LH are secreted by the anterior pituitary in response to gonadotropin-releasing hormone (GNRH) secreted by the hypothalamus. In both males and females, FSH and LH secretion is regulated by a balance of positive and negative feedback mechanisms involving the hypothalamic-pituitary axis, the reproductive organs, and the pituitary and sex steroid hormones. FSH and LH play a critical role in maintaining the normal function of the male and female reproductive systems. Abnormal FSH levels with corresponding increased or decreased levels of LH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased FSH levels are associated with menopause and primary ovarian hypofunction in females and primary hypogonadism in males. Decreased levels of FSH are associated with primary ovarian hyper-function in females and primary hypergonadism in males. Normal or decreased levels of FSH are associated with polycystic ovary disease in females. In males, LH is also called interstitial cell-stimulating hormone (ICSH). Abnormal LH levels with corresponding increased or decreased levels of FSH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased LH levels are associated with menopause, primary ovarian hypofunction, and polycystic ovary disease in females and primary hypo-gonadism in males. Decreased LH levels are associated with primary ovarian hyperfunction in females and primary hyper-gonadism in males.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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FSH and LH
7137