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Test Name

Oligoclonal Bands, CSF

CPT Code(s)

83916

Methodology

Isoelectric Focusing

Reference Range(s)

No bands
The clinical significance of a numerical band count, determined by isoelectric focusing, has not been definitively defined. The data should be interpreted in conjunction with all pertinent clinical and laboratory data for this patient.

Clinical Significance

Oligoclonal bands are present in the CSF of more than 85% of patients with clinically definite multiple sclerosis (MS). To distinguish between oligoclonal bands in the CSF due to a peripheral gammopathy and oligoclonal bands due to local production in the CNS, serum and CSF should be tested simultaneously. Oligoclonal bands can however, be observed in a variety of other diseases, e.g., subacute sclerosing panencephalitis, inflammatory polyneuropathy, CNS lupus, and brain tumors and infarctions.

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Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

127829P
674X
674
674
674
674
674X
674
674X
674X
22690
674
674
674
674
674
674
1418
674
674
674
22290
22290 OLIGOCLO
674X
OLICO IgG BANDS
674
127829P
674X
22690
674
6690
674
Oligoclonal Bands, CSF
674