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Test Name

PSA, Total

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CPT Code(s)**

84153
**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.

Methodology

Immunoassay (IA)

Limitations

Based on solid evidence, screening with PSA and/or DRE detects some prostate cancers that would never have caused important clinical problems. Current prostate cancer treatments, including radical prostatectomy and radiation therapy, result in permanent side effects in many men. The most common of these side effects are erectile dystunction and urinary incontinence. Whatever the screening modality, the screening process itself can lead to adverse psychological effects in men who have a prostate biopsy but do not have identified prostate cancer. Prostatic biopsies are associated with complications, including fever, pain, hematospermia/hematuria, positive urine cultures, and rarely sepsis. Lower PSA levels are associated with obesity.

Reference Range(s)

Male ≤4.0 ng/mL
Female Not established

Clinical Significance

Elevated serum PSA concentrations have been reported in men with prostate cancer, benign prostatic hypertrophy, and inflammatory conditions of the prostate.

Alternative Name(s)

Prostate Specific Antigen

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

5363
5363
5363
5363
5363
28571E
5363
5363X
5363
5363
5363
28571E
5363X
28571E
5363
5363
5363
5363
5363
5363
5363
5363X
5363
7458
5363
PSA, Total
5363