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Test Name

Estradiol

To view specimen requirements and codes please Select a regional laboratory.

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CPT Code(s)**

82670
**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.

Methodology

Immunoassay (IA)

Reference Range(s)

Female  
  Follicular Phase 19-144 pg/mL
  Mid-Cycle 64-357 pg/mL
  Luteal Phase 56-214 pg/mL
  Postmenopausal ≤31 pg/mL
Male ≤39 pg/mL

Clinical Significance

Measuring the circulating levels of estradiol is important for assessing the ovarian function and monitoring follicular development for assisted reproduction protocols. Estradiol plays an essential role throughout the human menstrual cycle. Elevated estradiol levels in females may also result from primary or secondary ovarian hyperfunction. Very high estradiol levels are found during the induction of ovulation for assisted reproduction therapy or in pregnancy. Decreased estradiol levels in females may result from either lack of ovarian synthesis (primary ovarian hypofunction and menopause) or a lesion in the hypothalamus-pituitary axis (secondary ovarian hypofunction). Elevated estradiol levels in males may be due to increased aromatization of androgens, resulting in gynecomastia.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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Estradiol
4021