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Scleroderma may be localized or diffuse (Progressive Systemic Sclerosis [PSS]) and may involve skin, gastrointestinal tracts, lungs, vascular and cardiac systems, and kidneys. PM-1 (PM-Scl) Antibody is present in approximately one-fourth of patients with the polymyositis/scleroderma overlap syndrome, 8% of patients with polymyositis alone and 2-5% of patients with scleroderma alone.
Polymyositis Associated Antibody
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