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HLA Typing for Narcolepsy
- Ordering Info
81383 (x2), 81377
Polymerase Chain Reaction (PCR) followed by Sequence Specific Oligonucleotide Probes (PCR-SSO)
See Laboratory Report
Narcolepsy is a multigenic environmentally influenced neurologic sleep disorder affecting 0.01 to 0.15% of the population. Among other genetic regions, it is associated with the HLA class LI region of the HLA complex. HLA-DQ6 and/or HLA-DR15 confer susceptibility to narcolepsy, with variable relative risk according to ethnicity.
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