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Legionella pneumophila Antibody (IgM), IFA
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Immunofluorescence Assay (IFA)
Legionella infection is associated with 2 clinically and epidemiologically distinct illnesses. Legionnaires disease and Pontiac fever. Legionnaires disease is characterized by fever, cough, myalgia, and pneumonia, whereas, Pontiac fever is a milder illness without pneumonia. Inhaling aerosols of water contaminated with Legionella species is believed to be the primary mode of Infection; the incubation period is generally 2-10 days. A 4-fold rise in IgG IFA Antibody titer to >1:128 between acute and convalescent sera may be used in the laboratory confirmation of Legionella infection.
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