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c-kit Mutation Analysis, Plasma-based, Leumeta®
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**IMPORTANT: CPT Code is informational only; obtain the Test Code for ordering.
Polymerase Chain Reaction (PCR) • Sequencing
Activating c-kit mutations have been identified in various human cancers. C-kit exon 8 and 17 mutations have been described in patients with CBF-AMLs and usually confer a poor prognosis with increased relapse rate. C-kit exon 9, 11, 13, 17 mutations have been reported in nearly 90% of GIST patients. The presence mutation usually predicts poor survival. C-kit exon 17 mutation has been reported in patients with systemic mastocytosis.
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.