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Test Name

HIV-1 Integrase Genotype

CPT Code(s)

87906

Methodology

Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) • Sequencing

Reference Range(s)

See Laboratory Report

Clinical Significance

The emergence of integrase drug resistance mutations has been observed in vitro and in patients experiencing virologic failure on raltegravir in clinical trials. Twenty three percent of patients receiving raltegravir in a clinical trial experienced virologic failure at 48 weeks and genotypic analysis detected raltegravir associated resistance mutations in 68% of viroligic failures. This assay amplifies and sequences the HIV-1 integrase gene and reports mutations at positions associated with integrase inhibitor drug resistance.

Test FAQ

HIV-1 Integrase Genotype

Alternative Name(s)

Isentress (Raltegravir, MK-0518) Resistance,HIV-1 Integrase Strand Transfer Inhibitor,Raltegravir,Elvitegravir,HIV-1 Integrase Mutations,MK-0518

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Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.

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HIV-1 Integrase Genotype
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