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Herpesvirus 6 Antibodies (IgG, IgM)

Test Code

9852N

CPT Code(s)

86790 (x2)

Preferred Specimen(s)

1 mL serum. Separate from cells as soon as possible.

Minimum Volume

0.5 mL

Transport Container

Plastic transport tube

Transport Temperature

Room temperature

Methodology

Immunofluorescence Assay

This assay was developed and its performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.

Reference Range(s)

IgG <1:10
IgM <1:20
Human Herpesvirus 6 (HHV-6) infects T-Lymphocytes, and has been identified as an etiologic agent of exanthema subitum. Rises in antibody titers to HHV-6 have been detected during infection with other viruses. In seroepidemiology studies of the prevalence of exposure using serum screening dilutions of 1:10, the detection of IgG antibody in a mid-life population approaches 100%.
Due to this high prevalence of HHV-6 Antibody, correlations of single IgG Titers with specific diseases are of little clinical value. Evidence of acute infection or reactivation of HHV-6 is demonstrated by a significant rise or seroconversion if IgG and IgM Titers.

Clinical Significance

HHV-6 is a distinct herpes virus that typically causes a self-limiting illness in patients who are not immunocompromised. In some patients, especially if immumocompromised, HHV-6 can cause febrile convulsions in infants, encephalitis mononucleosis-like symptoms, and hepatitis.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result
Code
Result NameLOINC CodeComponent Name
27145INTERPRETATION51730-0Herpes virus 6 Ab.IgG & IgM
6698HERPESVIRUS 6, IGG25416-9Herpes virus 6 Ab.IgG
8991HERPESVIRUS 6, IGM25417-7Herpes virus 6 Ab.IgM

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.