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Drug Toxicology Monitoring Alcohol Metabolites, with Confirmation, Urine

Test Code


CPT Code(s)



If Screen is Positive, a confirmation will be performed at an additional charge (CPT code(s): 80321 HCPCS: G0480).

Preferred Specimen(s)

1 mL random urine

Minimum Volume

0.5 mL

Collection Instructions

Avoid contact with ethanol, disinfectants, swabs

Specimen Container

Plastic, leak-proof container

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria

Preserved specimens


Screen: Immunoassay (IA) • Confirmation: Mass Spectrometry (MS)

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Setup Schedule

Set up: Mon-Sat evenings; Report available: 3 days

Reference Range(s)

Alcohol Metabolites <500 ng/mL
  Ethyl Glucuronide (ETG) <500 ng/mL
  Ethyl Sulfate (ETS) <100 ng/mL

Clinical Significance

Ethyl glucuronide and ethyl sulfate are metabolites of ethanol (alcohol) that may be present in urine after ingestion of, or exposure to, drinks, foods, medication or other products containing ethyl alcohol. Incidental exposure to alcohol-containing products such as mouthwash or hand sanitizer have also been shown to produce positive alcohol metabolites test results. LC-MS/MS testing detects EtG and EtS regardless of the source. Therefore, we encourage you to interpret alcohol metabolite test results in light of the clinical picture.

Alternative Name(s)


LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
84999990Confirm Test Performed At8262-8Service comment 02
86007755Alcohol Metabolites55349-5Ethyl glucuronide
86007756Ethyl Glucuronide (ETG)45324-1Ethyl glucuronide
86007757Ethyl Sulfate (ETS)60676-4Ethyl sulfate

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.