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PTH, Intact and Calcium

Test Code

8837

CPT Code(s)

82310, 83970

Preferred Specimen(s)

2 mL serum collected in a SST® (red-top) tube

Minimum Volume

1 mL

Collection Instructions

Spin to separate serum and transfer to plastic transport tube. Freeze immediately and submit to laboratory frozen. Do not submit glass tubes. Sodium or Lithium Heparin are no longer acceptable specimen types.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable

Refrigerated: Unacceptable

Frozen: 4 months

Reject Criteria

Gross hemolysis • Gross lipemia • Gross icterus • Received room temperature • Received refrigerated • Plasma

Methodology

PTH: Immunoassay (IA) • Calcium: Spectrophotometry (SP)

Performing Laboratory

Quest Diagnostics Nichols Institute

33608 Ortega Highway

San Juan Capistrano, CA 92690-6130

Setup Schedule

Set up: 5 days a week a.m.; Report available: 2 days

Reference Range(s)

 Calcium Male Female
<1 month: 8.4-10.6 8.4-10.6
1-11 months: 8.7-10.5 8.7-10.5
1-3 years: 8.5-10.6 8.5-10.6
4-19 years: 8.9-10.4 8.9-10.4
20-49 years: 8.6-10.3 8.6-10.2
>49 years: 8.6-10.3 8.6-10.4
Intact PTH  
<6 Years Not established
6-9 Years 9-59 pg/mL
10-13 Years 11-74 pg/mL
14-17 Years 9-69 pg/mL
>17 Years 10-65 pg/mL
Interpretive Guide
  Intact PTH Calcium 
Normal Parathyroid Normal Normal
Hypoparathyroidism Low or Low Normal Low
Hyperparathyroidism     
  Primary Normal or High High
  Secondary High Normal or Low
  Tertiary High High
Non-Parathyroid    
  Hypercalcemia Low or Low Normal High

Clinical Significance

The assay is useful in making the diagnosis of primary hyperparathyroidism, secondary hyperparathyroidism, and a differential diagnosis of hypercalcemia. The assay helps in distinguishing hypercalcemia cause by either primary hyperparathyroidism or malignant disease.


Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.)

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.