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Protein, Total, 24-Hour Urine with Creatinine

Test Code


CPT Code(s)

82570, 84156

Preferred Specimen(s)

10 mL aliquot from a well-mixed, 24-hour collection - no preservative

Minimum Volume

2 mL

Alternative Specimen(s)

Urinalysis transport tube (yellow-top, blue fill line, preservative tube)

Collection Instructions

Record total volume and duration of collection on test requisition and urine vial

Transport Container

Plastic urine container

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 5 days
Frozen: 30 days

Reject Criteria

Acidified urine


Spectrophotometry (SP) • Colorimetric

Performing Laboratory

Quest Diagnostics-Seattle
1737 Airport Way S Suite 200
Seattle, WA 98134-1636

Setup Schedule

Set up: Tues-Sat; Report available: 4 days


Requires accurate 24-hour urine collection.

Reference Range(s)

Protein, Total, 24-Hour Urine <150 mg/24 h
Protein/Creatinine Ratio ≤84 mg/g creat
Creatinine, 24-Hour Urine  
<36 Months Not established
3-8 Years 0.11-0.68 g/24 h
9-12 Years 0.17-1.41 g/24 h
13-17 Years 0.29-1.87 g/24 h
>17 Years 0.63-2.50 g/24 h

Clinical Significance

Proteinuria, mainly glomerular, is often a manifestation of primary renal disease although transient proteinuria may occur with fevers, thyroid disorders, and in heart disease. In the absence of renal disease, the degree of proteinuria is slight, usually amounting to less than 2 grams per day. In chronic glomerulonephritis and in the nephrotic syndrome including lipoid nephrosis and in some forms of hypertensive vascular disease, protein loss may vary from a few grams to as much as 30 g/day.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
25025500URINE CREATININE (MG/DL)20624-3Creatinine
25025900CREATININE, 24 HOUR URINE2162-6Creatinine
50053700PROTEIN, TOTAL (MG/DL)21482-5Protein
50054550PROTEIN/CREATININE RATIO13801-6Protein/Creatinine
50054600PROTEIN, TOTAL, 24 HR UR2889-4Protein

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.