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PORPHYRINS,FRACT,QN,24 HOUR UR

Test Code

729X

CPT Code(s)

84120

Includes

Coproporphyrin I, Coproporphyrin III, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Total Porphyrins, Uroporphyrin I, Uroporphyrin III

Preferred Specimen(s)

Preferred Specimen Volume: 2 ml
Specimen Type ALIQUOT OF A WELL-MIXED 24 HR. URINE
Specimen State Refrigerated (cold packs)
24-hour urine collected with 5 grams of sodium carbonate,
refrigerated and protected from light during collection is
preferred. Collection with no preservative is acceptable, if
properly refrigerated and light protected. 24-hour total
volume must be provided on the test request form.


STABILITY:
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Minimum Volume

1 ml

Transport Container

UrineLight Protected

Methodology

High Performance Liquid Chromatography (HPLC)

Performing Laboratory

960-SJC,NICHOLS QUEST DIAGNOSTICS

Setup Days

T,W,TH,F,SN

Report Available

6 DAYS

Reference Range(s)

Adult Reference Ranges  
Uroporphyrin I 4.1-22.4 mcg/24 h
Uroporphyrin III 0.7-7.4 mcg/24 h
Heptacarboxyporphyrin ≤3.3 mcg/24 h
Hexacarboxyporphyrin ≤10 mcg/24 h
Pentacarboxyporphyrin ≤4.6 mcg/24 h
Coproporphyrin I 7.1-48.7 mcg/24 h
Coproporphyrin III 11.0-148.5 mcg/24 h
Total Porphyrins 35-210.7 mcg/24 h

Clinical Significance

Porphyria is a group of distinct disorders characterized by the abnormal accumulation of porphyrins or porphyrin precursors. Porphyrin Fractionation of Urine is useful in diagnosing porphyrin cutanea tarda, hereditary coproporphyria, and variegate porphyria.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result
Code
Result NameLOINC CodeComponent Name
Z7483PENTACARBOXYLPORPHYRIN9730-3Pentacarboxylporphyrins
Z7529HEXACARBOXYLPORPHYRIN9527-3Hexacarboxylporphyrin
Z7535HEPTACARBOXYLPORPHYRIN24462-4Heptacarboxylporphyrin
Z7775PORPHYRINS,TOTAL10885-2Porphyrins
Z81174TOTAL VOLUME3167-4Specimen volume
Z81175INTERPRETATIONPending assignment
Z82028UROPORPHYRIN IPending assignment
Z82029UROPORPHYRIN IIIPending assignment
Z82030COPROPORPHYRIN I6877-5Coproporphyrin 1
Z82031COPROPORPHYRIN III6878-3Coproporphyrin 3

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.