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FSH and LH

Test Code

7137

CPT Code(s)

83001,83002

Preferred Specimen(s)

2 mL serum

Minimum Volume

1 mL

Transport Container

Serum Separator Tube (SST®)

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days

Methodology

Immunoassay (IA)

Reference Range(s)

FSH

Male 1.6-8.0 mIU/mL
Female    
  Follicular Phase 2.5-10.2 mIU/mL
  Mid-Cycle Peak 3.1-17.7 mIU/mL
  Luteal Phase 1.5- 9.1 mIU/mL
  Postmenopausal   23.0-116.3  mIU/mL
Children (<18 years old): FSH reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, the Quest Diagnostics FSH, Pediatrics assay is recommended (test code 36087).

LH
Male    
18-59 Years 1.5-9.3 mIU/mL
≥60 Years 1.6-15.2 mIU/mL
Female    
  Follicular Phase 1.9-12.5 mIU/mL
  Mid-Cycle Peak 8.7-76.3 mIU/mL
  Luteal Phase 0.5-16.9 mIU/mL
  Postmenopausal 10.0-54.7 mIU/mL
Children (<18 years old): LH reference ranges established on post-pubertal patient population. Reference range not established for pre-pubertal patients using this assay. For pre-pubertal patients, the Quest Diagnostics LH, Pediatrics assay is recommended (test code 36086).

Clinical Significance

FSH and LH are secreted by the anterior pituitary in response to gonadotropin-releasing hormone (GNRH) secreted by the hypothalamus. In both males and females, FSH and LH secretion is regulated by a balance of positive and negative feedback mechanisms involving the hypothalamic-pituitary axis, the reproductive organs, and the pituitary and sex steroid hormones. FSH and LH play a critical role in maintaining the normal function of the male and female reproductive systems. Abnormal FSH levels with corresponding increased or decreased levels of LH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased FSH levels are associated with menopause and primary ovarian hypofunction in females and primary hypogonadism in males. Decreased levels of FSH are associated with primary ovarian hyper-function in females and primary hypergonadism in males. Normal or decreased levels of FSH are associated with polycystic ovary disease in females. In males, LH is also called interstitial cell-stimulating hormone (ICSH). Abnormal LH levels with corresponding increased or decreased levels of FSH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased LH levels are associated with menopause, primary ovarian hypofunction, and polycystic ovary disease in females and primary hypo-gonadism in males. Decreased LH levels are associated with primary ovarian hyperfunction in females and primary hyper-gonadism in males.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result
Code
Result NameLOINC CodeComponent Name
55058200FSH15067-2Follitropin
55058300LH10501-5Lutropin

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.