ANCA Screen with Reflex to ANCA Titer [70171X]

CPT Code(s)

86021

Includes

If  ANCA Screen is positive, C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer will be performed at an additional charge (CPT code(s): 86021 for each titer performed).

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Alternative Specimen(s)

1 mL serum (Min 0.5 mL) Serum Separator Tube

Specimen Container

Red-top tube (no gel)

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days

Refrigerated: 14 days

Frozen: 30 days

Reject Criteria

Gross hemolysis • Gross lipemia

Methodology

Immunoassay

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

Setup Schedule

Set up: Mon-Fri Afternoon; Report available: 3 days

Reference Range(s)

ANCA Screen

Negative

ANCA Screen includes evaluation for P-ANCA, C-ANCA, and atypical P-ANCA.

C-ANCA Titer	<1:20
P-ANCA Titer	<1:20
Atypical P-ANCA Titer	<1:20

Clinical Significance

Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and/or C-ANCA and/or atypical P-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases, inflammatory bowel disease, as well as other autoimmune diseases.

Alternative Names(s)

ANCA