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Carnitine, Total; Carnitine, Free; Carnitine, Esters; Esterified/Free Ratio
Patient should be in a well-fed state
1 mL serum
Plasma collected in a sodium heparin (green-top) tube
Collect blood sample in serum (red-top) tube. Separate serum by centrifugation. Avoid hemolysis. Remove serum and place in plastic tube. Freeze immediately after separation.
Room temperature: 5 hours
Refrigerated: 5 days
Frozen: 30 days
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
Set up: 4 days a week p.m.; Report available: 3 days
|Adult Male||30-70 µmol/L|
|Adult Female||25-58 µmol/L|
|Male ≤17 Years||32-62 µmol/L|
|Female ≤17 Years||28-59 µmol/L|
|Adult Male||23-59 µmol/L|
|Adult Female||19-48 µmol/L|
|Male ≤17 Years||25-54 µmol/L|
|Female ≤17 Years||19-51 µmol/L|
|Adult Male||4-15 µmol/L|
|Adult Female||4-13 µmol/L|
|Male ≤17 Years||4-12 µmol/L|
|Female ≤17 Years||3-16 µmol/L|
|Male ≤17 Years||0.09-0.35|
|Female ≤17 Years||0.09-0.49|
Serum carnitine analysis is useful in the diagnosis and monitoring of patients with carnitine deficiency (either primary or secondary). Primary carnitine deficiency is an autosomal recessively inherited genetic condition that affects carnitine uptake by cells and tissues through a defect in the plasma membrane carnitine transporter. Secondary carnitine deficiency can be seen in some disease states or in patients on carnitine-poor diets, but is also seen in a number of metabolic disorders. In these disorders, carnitine complexes with the accumulated substrate of the blocked metabolic step, and the resulting acylcarnitine ester is excreted in the urine, leading to a depletion of carnitine in the patient.
The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.NOTE: The codes listed in the table below are not orderable Test Codes.
|Result Name||LOINC Code||Component Name|
|10563||Carnitine, Free||14286-9||Carnitine.free (C0)|
|10564||Carnitine, Esters||19074-4||Carnitine esters|
|27135||Esterified/Free Ratio||40869-0||Carnitine esters/Carnitine.free (C0)|
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.
* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.