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Lactic Acid, Plasma

Test Code


CPT Code(s)


Patient Preparation

Sample should be collected without the use of a tourniquet, avoid hand-clenching. If a tourniquet has been used, it should be released for one minute prior to drawing blood. Collected blood should be cooled on ice immediately and separated from the cells within 3 hours.

Preferred Specimen(s)

2 mL frozen plasma from a gray-top tube

Minimum Volume

0.5 mL

Alternative Specimen(s)


Collection Instructions

The collected blood should be well-mixed and separated from the cells within 3 hours. Freeze plasma and ship frozen.

The assay manufacturer, Roche, notes that N-acetylcysteine, when administered in high concentrations (such as for treatment of acetaminophen overdose), can interfere with their assay for Lactate (Lactic Acid), leading to falsely low results.

Transport Container

Transport tube

Transport Temperature


Specimen Stability

Room temperature: 3 hours
Refrigerated: 7 days
Frozen: 90 days

Reject Criteria

Gross hemolysis • Specimens with visible icterus


Spectrophotometry (SP)

Performing Laboratory

Quest Diagnostics Nichols Institute-Chantilly VA
14225 Newbrook Drive
Chantilly, VA 20151-2228

Setup Schedule

Set up: Sun-Fri

Reference Range(s)

4-16 mg/dL

Clinical Significance

Lactic acid is the endproduct of the anaerobic metabolism of glucose. The blood lactic acid concentration is affected by its production in muscle cells and erythrocytes and its rate of metabolism in the liver. During exercise, blood lactate can increase up to ten times of normal levels.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
50027500LACTIC ACID, PLASMA14118-4Lactate

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.