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Culture, Ureaplasma urealyticum

Test Code


CPT Code(s)


Preferred Specimen(s)

Minimum: 1 mL or 1 swab of urogenital specimen (vaginal, cervical, urethral swabs or vaginal secretions) collected in VCM medium (green-top), or M4 Tranpsort Media, or UTM

Alternative Specimen(s)

Urine, sterile body fluids, tissue, wounds (swab), respiratory (sputum, bronchial washing, tracheobronchial secretions, bronchial alveolar lavage, nasopharyngeal or throat swabs) collected in a VCM medium (green-cap) tube or equivalent (UTM) container (see instructions)

Collection Instructions

Ship on dry ice.
Client should centrifuge urine at 3000 rpm for 15 minutes. Suspend sediment in VCM or equivalent transport media.

If the specimen is not centrifuged, submit a 1:1 volume of urine in VCM or equivalent transport media.

Submit a 1:1 volume of sterile body fluids, tissue, respiratory (sputum, bronchial washing, tracheobronchial secretions, bronchial alveolar lavage) in VCM or equivalent transport media.

Respiratory samples are only acceptable from children under 1 year old.

Please note: Do not use M4RT; the room temperature formula cannot be used for mycoplasma.

Specimen Container

VCM medium (green-top), or M4 Tranpsort Media, or UTM

Transport Temperature

Frozen -70°C

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 48 hours
Frozen -30° C: Unacceptable
Frozen -70° C: 30 days

Reject Criteria

Specimens collected on wooden shafted swabs, or cotton swabs • Specimens received in expired transport medium • Tissue specimens in formalin • Urine containing any preservatives • Specimens received in M4RT transport medium • Raw specimens



Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Setup Schedule

Set up: Daily a.m., p.m., and (night shifts); Report available: 10 days

Reference Range(s)

Not isolated

Clinical Significance

Ureaplasma urealyticum and Mycoplasma hominis are primarily associated with genital tract colonization and disease in adults and respiratory tract colonization and disease in newborns. Though controversial, these organisms have been associated with endometritis, chorioamnionitis, premature rupture of membranes, stillbirth, premature birth, low birth weight, post-partum infections, and infertility. Of particular concern is the causal relationship between central nervous system infections in the premature newborn and U. urealyticum.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.