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To view specimen requirements and codes please select your laboratory:

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Creatine Kinase (CK), Total

Test Code


CPT Code(s)


Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Alternative Specimen(s)

Plasma collected in: Sodium heparin (green-top) or lithium heparin (green-top) tube

Collection Instructions

If CK and CK Isoenzymes are ordered together, specimen must be submitted frozen

Transport Container

Serum Separator Tube (SST®)

Transport Temperature

Room temperature

Specimen Stability

Serum and plasma
 Room temperature: 72 hours
 Refrigerated: 7 days
 Frozen: 28 days

Reject Criteria

Gross hemolysis • Anticoagulants other than heparin


Spectrophotometry (SP)

Performing Laboratory

Quest Diagnostics - Southwest Region

Setup Schedule

Set up: Mon-Sat; Report available:3 days

Reference Range(s)

Age Male (U/L) Female (U/L)
≤3 Days (newborn) <1578 <1578
28 Days <183 <134
11 Months <136 <143
6 Years <160 <143
9 Years <177 <143
12 Years <217 <143
18 Years <245 <143
>18 Years 44-196 29-143

Clinical Significance

Test for myocardial infarction and skeletal muscle damage. Elevated results may be due to: Myocarditis, Mycardial Infarction (heart attack), Muscular Dystrophy, Muscle Trauma or excessive exercise.

Alternative Name(s)


LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
25014100CREATINE KINASE, TOTAL2157-6Creatine kinase
25016000LIPEMIA20394-3Sample lipemic
25016100ICTERUS20392-7Sample icteric
25016200HEMOLYSIS20393-5Sample hemolyzed

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.