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Estradiol, Ultrasensitive, LC/MS/MS

Test Code


CPT Code(s)


Preferred Specimen(s)

0.5 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.2 mL

Collection Instructions

Specify age and sex on test request form.

Transport Temperature


Specimen Stability

Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 2 years
Frozen -70°C: 3 years

Reject Criteria

Received room temperature • Serum separator tube • Moderate to gross hemolysis • Lipemia • Animal specimen


Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Performing Laboratory

Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675

Setup Schedule

Set up: Sun-Fri nights; Report available: 3-6 days

Reference Range(s)

Male ≤29 pg/mL
  Follicular Stage 39-375 pg/mL
  Luteal Stage 48-440 pg/mL
  Postmenopausal ≤10 pg/mL

Pediatric Male (pg/mL) Female (pg/mL)
Pre-pubertal (1-9 Years) ≤4 ≤16
10-11 Years ≤12 ≤65
12-14 Years ≤24 ≤142
15-17 Years ≤31 ≤283

Clinical Significance

Diagnostic applications of estradiol assays include assessment of ovarian function in a wide variety of situations (menstrual disorders, precocious or delayed puberty, assisted reproduction protocols). For men, estradiol measurement may be useful in the evaluation of gynecomastia.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
30289Estradiol, Ultrasensitive, LC/MS/MS35384-7Estradiol
ASTMRCVDResults Received19146-0Reference lab test results

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.