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Antiphospholipid Syndrome Diagnostic Panel [19872X]

Test Code

19872

CPT Code(s)

85613, 85730, 86146 (x3), 86147 (x3)

Includes

Cardiolipin IgG, IgM, IgA; B2-Glycoprotein I IgG, IgM, IgA; Lupus Anticoagulant Evaluation with Reflex

Lupus Anticoagulant Evaluation with Reflex:
If PTT-LA is >40 seconds, Hexagonal Phase Confirmation will be performed at an additional charge (CPT code(s): 85598).
If dRVVT is >45 seconds, dRVVT Confirmation will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirmation is positive, dRVVT 1:1 dilution will be performed at an additional charge (CPT code(s): 85613).

Preferred Specimen(s)

3 mL frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube

Minimum Volume

2 mL

Specimen Container

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria

Hemolysis • Specimens received room temperature or refrigerated • Serum

Methodology

Immunoassay (IA) • Photo-Optical Clot Detection

Performing Laboratory

Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Setup Schedule

Set up: Varies; Report Available: 4 days

Reference Range(s)

See individual tests

Clinical Significance

This assay may be useful in supporting or ruling out a diagnosis of antiphospholipid syndrome.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result
Code
Result NameLOINC CodeComponent Name
4662Cardiolipin Ab (IgG)3181-5Cardiolipin Ab.IgG
4661Cardiolipin Ab (IgA)5076-5Cardiolipin Ab.IgA
4663Cardiolipin Ab (IgM)3182-3Cardiolipin Ab.IgM
14357APTT-LA Screen34571-0Coagulation surface induced.lupus sensitive
143583Hexagonal Phase Confirm.33930-9Lupus anticoagulant neutralization.hexagonal phase phospholipid
143593dRVVT Confirmation52756-4Coagulation dilute Russell viper venom induced.excess phospholipid
145653ALupus Anticoagulant Eval.3281-3Lupus anticoagulant
33693CdRVVT 1:1 Mix34569-4Coagulation dilute Russell viper venom induced.factor substitution^immediately after 1:2 addition of normal plasma
3369AdRVVT Screen6303-2Coagulation dilute Russell viper venom induced
3369CdRVVT6303-2Coagulation dilute Russell viper venom induced
3369IdRVVT Mix Interpretation:50008-2Mixing studies
883Thrombin Clotting TimePending assignment
36552Beta2-Glycoprotein I (IgA)21108-6Beta 2 glycoprotein 1 Ab.IgA
36553Beta2-Glycoprotein I (IgM)16136-4Beta 2 glycoprotein 1 Ab.IgM
36554Beta2-Glycoprotein I (IgG)16135-6Beta 2 glycoprotein 1 Ab.IgG

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.