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Antiphospholipid Syndrome Diagnostic Panel [19872X]
85613, 85730, 86146 (x3), 86147 (x3)
Cardiolipin IgG, IgM, IgA; B2-Glycoprotein I IgG, IgM, IgA; Lupus Anticoagulant Evaluation with Reflex
Lupus Anticoagulant Evaluation with Reflex:
If PTT-LA is >40 seconds, Hexagonal Phase Confirmation will be performed at an additional charge (CPT code(s): 85598).
If dRVVT is >45 seconds, dRVVT Confirmation will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirmation is positive, dRVVT 1:1 dilution will be performed at an additional charge (CPT code(s): 85613).
3 mL frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube
Centrifuge light blue-top tube 15 minutes at approx. 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial.
Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.
Plastic screw-cap vial
Room temperature: Unacceptable
Frozen: 30 days
Hemolysis • Grossly lipemic • Serum
Immunoassay (IA) • Photo-Optical Clot Detection
|Quest Diagnostics Nichols Institute|
|14225 Newbrook Drive|
|Chantilly, VA 20153|
Set up: Varies; Report Available: 4 days
See individual tests
This assay may be useful in supporting or ruling out a diagnosis of antiphospholipid syndrome.
The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.NOTE: The codes listed in the table below are not orderable Test Codes.
|Result Name||LOINC Code||Component Name|
|4662||Cardiolipin Ab (IgG)||3181-5||Cardiolipin Ab.IgG|
|4661||Cardiolipin Ab (IgA)||5076-5||Cardiolipin Ab.IgA|
|4663||Cardiolipin Ab (IgM)||3182-3||Cardiolipin Ab.IgM|
|14357A||PTT-LA Screen||34571-0||Coagulation surface induced.lupus sensitive|
|143583||Hexagonal Phase Confirm.||33930-9||Coagulation surface induced.hexagonal phase phospholipid|
|143593||dRVVT Confirmation||52756-4||Coagulation dilute Russell viper venom induced.excess phospholipid|
|145653A||Lupus Anticoagulant Eval.||3281-3||Lupus anticoagulant|
|33693C||dRVVT 1:1 Mix||75513-2||DRVVT with 1:1 Pooled Normal Plasma|
|3369A||dRVVT Screen||6303-2||Coagulation dilute Russell viper venom induced|
|3369C||dRVVT||6303-2||Coagulation dilute Russell viper venom induced|
|3369I||dRVVT Mix Interpretation:||50008-2||Mixing studies|
|883||Thrombin Clotting Time||3243-3||Coagulation thrombin induced|
|36552||Beta2-Glycoprotein I (IgA)||21108-6||Beta 2 glycoprotein 1 Ab.IgA|
|36553||Beta2-Glycoprotein I (IgM)||16136-4||Beta 2 glycoprotein 1 Ab.IgM|
|36554||Beta2-Glycoprotein I (IgG)||16135-6||Beta 2 glycoprotein 1 Ab.IgG|
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.
* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.