GlycoMark^®

CPT Code(s)

84378

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Alternative Specimen(s)

Plasma collected in an EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days

Refrigerated: 7 days

Frozen: 28 days

Reject Criteria

Gross hemolysis • Anticoagulants other than EDTA

Methodology

Colorimetric (C) • Enzymatic

Performing Laboratory

Quest Diagnostics Nichols Institute

33608 Ortega Highway

San Juan Capistrano, CA 92690-6130

Setup Schedule

Set up: Tues-Sat; Report Available: 2-5 days

Reference Range(s)

≤1 Year	Not established
2-17 Years Male	15.0-38.0	µg/mL
2-17 Years Female	11.2-35.7	µg/mL
≥18 Years Male	7.3-36.6	µg/mL
≥18 Years Female	7.5-28.4	µg/mL

GlycoMark^® reference ranges apply to persons without diabetes. In people with diabetes, under good to moderate glycemic control (Hemoglobin A1c levels ≤8%), GlycoMark^® levels <8 µg/mL suggest significant glycemic variability, most likely due to post meal blood glucose levels increasing above 180 mg/dL.

Clinical Significance

Measures 1,5 anhydroglucitol, a glucose derived carbohydrate whose urinary excretion varies inversely with mean blood glucose. 1,5 anhydroglucitol appears to integrate variation in mean blood glucose over a period of about two weeks.