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To view specimen requirements and codes please select your laboratory:
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Prometheus(R) Celiac PLUS
81382 (x2), 82784, 83520 (x3), 86255
5 mL whole blood collected in an EDTA (lavender-top) tube
2.0 mL serum collected in a red-top tube (no gel)
0.5 mL serum; 5 mL whole blood
Both Celiac Genetics (HLA DQ2/DQ8) and Celiac Serology will be performed. Both serum AND whole blood specimens are required for this test.
Plastic screw-cap vial and Lavender Top EDTA Tube
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Room temperature: Not established
Refrigerated: 8 days
Therapeutics and Diagnostics
9410 Carroll Park Drive
San Diego, CA 92121
Set up: Mon-Fri a.m.; Report available: 11 days
Most celiac patients carry either the DQ2 (about 9 5% of celiacs) or the DQ8 haplotype (about 5% of celiacs). There are two DQ2 haplotypes, but only one DQ8 haplotype-specific combination that may confer different risks for the development of celiac disease, as shown above(3).
1) Pietzak M, et al., Stratifying Risk for Celiac Disease in a Large At-Risk United States Population by Using HLA Alleles. Clin Gastroenterol Hepatol. 2009; 7:966 - 971.
2) Fasano A, Berti I, et al., Prevalence of celiac disease in at-risk and not at-risk groups in the United States: a large multicenter study. Arch Intern Med. 2003; 163: 286-292.
3) Koning F, Schuppan D, Cerf-Bensussan N, Sollid LM, Pathomechanisms in celiac disease. Best Pract Res Clin Gastroenterol. 2005; 19: 373-387.
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.)
* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.