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To view specimen requirements and codes please select your laboratory:

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Hepatitis C Virus (HCV) FibroSURE

Test Code


CPT Code(s)

82172, 82247, 82977, 83010, 83883, 84460 or 0001M*
*The 2014 AMA CPT codebook contains the component CPT codes and the new MAAA codeset. Please direct any questions regarding coding to the payor being billed.

Patient Preparation

Patient should fast for at least eight hours

Preferred Specimen(s)

3 mL serum

Minimum Volume

3 mL

Collection Instructions

Patient age and sex must be included on the test requisition. Separate serum from cells within one hour of collection. To avoid delays in turn-around time, please submit separate frozen specimens for each test when requesting multiple tests on frozen specimens.
Note: Patient must be over 14 years old.

Transport Container

Plastic screw-cap vial

Transport Temperature


Specimen Stability

Room temperature: Unacceptable
Refrigerated: 72 hours
Frozen: 4 months

Reject Criteria

Gross hemolysis • Gross lipemia • Improperly labeled specimen


Colorimetric (C) • Immunologic • Kinetic • Nephelometry

This test was developed and its performance characteristics have been determined by LabCorp. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary.

Performing Laboratory

1440 York Court
Burlington, NC 27215-3361

Reference Range(s)

See Laboratory Report

Clinical Significance

Assessment of liver status following a diagnosis of HCV. Baseline determination of liver status before initiating HCV therapy. Post-treatment assessment of liver status six months after completion of therapy. Noninvasive assessment of liver status in patients who are at increased risk of complications from a liver biopsy.

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
86003671FIBROSIS SCORE48795-9Fibrosis score
86003672FIBROSIS STAGE48794-2Fibrosis stage
86003673NECROINFLAMMAT ACT. SCORE48792-6Necroinflammatory activity score
86003674NECROINFLAMMAT ACT. GRADE48793-4Necroinflammatory activity grade
86003675ALPHA 2 MACROGLOBULINS,QN1835-8Alpha-2-Macroglobulin
86003677APOLIPOPROTEIN A 11869-7Apolipoprotein A-I
86003678BILIRUBIN, TOTAL1975-2Bilirubin
86003679GGT2324-2Gamma glutamyl transferase
86003680ALT (SGPT)1742-6Alanine aminotransferase

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.