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SurePath™ Pap reflex HPV mRNA E6/E7, C. trachomatis, N. gonorrhoeae

Test Code


CPT Code(s)

87491, 87591, 88142 (HCPCS: G0123)


SurePath™ Pap reflex HPV mRNA E6/E7
Chlamydia/Neisseria gonorrhoeae RNA, TMA

If SurePath™ Pap result is ASCUS, HPV mRNA E6/E7 will be performed at an additional charge (CPT code(s): 87624).

Pap results requiring physician interpretation will be performed at an additional charge (CPT code(s): 88141; HCPCS: G0124)
For Interpretations of Atypical Squamous Cells (ASC), HPV mRNA E6/E7, will be performed at an additional charge (CPT code(s): 87624).

Preferred Specimen(s)

Pap sample collected with a cytobroom or cytobrush and spatula. Cytobroom tip submitted in a SurePath™ vial.

Minimum Volume

1 SurePath™ vial

Transport Container

SurePath™ vial

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 4 days
Frozen: Unacceptable

Reject Criteria

Unlabeled vial • Leakage of fluid during transport • Mismatch between name of patient on vial and name on test requisition • SurePath™ (blue) vials without the head of the collection device(s) in the fluid • Expired vial


See individual tests

Performing Laboratory

Quest Diagnostics - Southwest Region

Reference Range(s)

See Laboratory Report

LOINC®' Code(s)

The Result and LOINC information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table below are not orderable Test Codes.

Result NameLOINC CodeComponent Name
90000225SOURCE:19763-2Specimen source
90000555REPORT STATUS:8251-1Service comment
90000571CLINICAL INFORMATION:55752-0Clinical information
90000597LMP:8665-2Date last menstrual period
90000613PREV. PAP:60432-2Date of previous PAP smear
90000639PREV. BX:60431-4Date of previous biopsy
90000654NUMBER OF SLIDES42186-7Number of specimens received
90000712STATEMENT OF ADEQUACY:19764-0Statement of adequacy
90000779GENERAL CATEGORIZATION:19762-4General categories
90001256INTERPRETATION/RESULT:10524-7Microscopic observation
90001280COMMENT:19774-9Cytology study comment
90001496COMMENT, INTERNAL8251-1Service comment
90020959REVIEW CYTOTECHNOLOGIST:19767-3Cytologist
90021122INFECTION:49034-2Microorganism identified
70043800CHLAMYDIA TRACHOMATIS RNA, TMA43304-5Chlamydia trachomatis rRNA
70043900NEISSERIA GONORRHOEAE RNA, TMA43305-2Neisseria gonorrhoeae rRNA

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.